Silver nanoparticles deposited on graphene oxide for ultrasensitive surface-enhanced Raman scattering immunoassay of cancer biomarker

Nanoscale ◽  
2018 ◽  
Vol 10 (25) ◽  
pp. 11942-11947 ◽  
Author(s):  
Lin Yang ◽  
Shu Jun Zhen ◽  
Yuan Fang Li ◽  
Cheng Zhi Huang

An ultrasensitive surface-enhanced Raman scattering (SERS) immunoassay of prostate specific antigen (PSA) is developed by introducing a common enzyme-induced dissolution reaction of AgNPs on the surface of graphene oxide (GO), which decreases the Raman signal of GO.

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Li Yuan ◽  
Jinghuai Fang ◽  
Yonglong Jin ◽  
Chaonan Wang ◽  
Tian Xu

We fabricated a simple, cheap, and functional surface enhanced Raman scattering substrate for biomedical application. Hot spots between two close silver nanoparticles distributed in the skeleton of a three-dimensional porous membrane, especially in the pores, were formed. The dual poles of micropores in the membrane were discussed. The pores could protect the silver nanoparticles in the pores from being oxidized, which makes the membrane effective for a longer period of time. In addition,Staphylococcus aureuscells could be trapped by the micropores and then the Raman signal became stronger, indicating that the functional surface enhanced Raman scattering substrate is reliable.


2006 ◽  
Vol 496 (2) ◽  
pp. 281-287 ◽  
Author(s):  
Huiying Jia ◽  
Jiangbo Zeng ◽  
Wei Song ◽  
Jing An ◽  
Bing Zhao

Sign in / Sign up

Export Citation Format

Share Document