scholarly journals A Biomedical Surface Enhanced Raman Scattering Substrate: Functionalized Three-Dimensional Porous Membrane Decorated with Silver Nanoparticles

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Li Yuan ◽  
Jinghuai Fang ◽  
Yonglong Jin ◽  
Chaonan Wang ◽  
Tian Xu
Keyword(s):  
Silver Nanoparticles ◽  
Raman Scattering ◽  
Three Dimensional ◽  
Surface Enhanced Raman Scattering ◽  
Porous Membrane ◽  
Raman Signal ◽  
Functional Surface ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

We fabricated a simple, cheap, and functional surface enhanced Raman scattering substrate for biomedical application. Hot spots between two close silver nanoparticles distributed in the skeleton of a three-dimensional porous membrane, especially in the pores, were formed. The dual poles of micropores in the membrane were discussed. The pores could protect the silver nanoparticles in the pores from being oxidized, which makes the membrane effective for a longer period of time. In addition,Staphylococcus aureuscells could be trapped by the micropores and then the Raman signal became stronger, indicating that the functional surface enhanced Raman scattering substrate is reliable.

Three-Dimensional Surface-Enhanced Raman Scattering Substrate Fabricated Using Chemical Decoration of Silver Nanoparticles on Electrospun Polycarbonate Nanofibers

2016 ◽  
Vol 71 (5) ◽  
pp. 879-887 ◽  
Author(s):  
Murugesan Balamurugan ◽  
Jyisy Yang
Keyword(s):  
Silver Nanoparticles ◽  
Raman Scattering ◽  
High Efficiency ◽  
Three Dimensional ◽  
Surface Enhanced Raman Scattering ◽  
Simple Method ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

In this work, a simple method via decoration of silver nanoparticles (AgNPs) on electrospun polycarbonate nanofibers (PCNFs) was proposed to prepare highly sensitive three-dimensional (3D) substrates for surface-enhanced Raman scattering (SERS) measurements. The method proposed in this work gave a high sensitive Ag@PCNFs substrate, which resulted from a successful production of high surface area of PCNFs with a high efficiency in the decoration of AgNPs. To produce PCNFs suitable for SERS application, parameters in fabrication of PCNFs were systematically examined and correlated with their corresponding scanning electron microscope (SEM) images. Examined parameters included the concentration of PC solution, the solvent to form PC solution, the applied voltage, and the rotating speed of a drum collector. Using the optimized condition, the bead-free PCNFs with a diameter in the range of 200–400 nm were successfully produced. To increase the efficiency in decoration of AgNPs, the surface properties of PNCFs were altered with an organic solvent, which was selected experimentally with guidance of Hildebrand solubility parameter. Results indicated that methanol was the most suitable solvent to effectively decorate AgNPs on PCNFs. By probing with para-hydroxythiophenol (pHTP), prepared SERS substrates of Ag@PCNFs provided an enhancement factor to the order of 7, which is at least an order of magnitude larger than the reported values in the literature for SERS substrates prepared with the electrospinning technique.

Silver nanoparticles deposited on graphene oxide for ultrasensitive surface-enhanced Raman scattering immunoassay of cancer biomarker

Nanoscale ◽  
2018 ◽  
Vol 10 (25) ◽  
pp. 11942-11947 ◽  
Author(s):  
Lin Yang ◽  
Shu Jun Zhen ◽  
Yuan Fang Li ◽  
Cheng Zhi Huang
Keyword(s):  
Silver Nanoparticles ◽  
Graphene Oxide ◽  
Raman Scattering ◽  
Specific Antigen ◽  
Surface Enhanced Raman Scattering ◽  
Raman Signal ◽  
Dissolution Reaction ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

An ultrasensitive surface-enhanced Raman scattering (SERS) immunoassay of prostate specific antigen (PSA) is developed by introducing a common enzyme-induced dissolution reaction of AgNPs on the surface of graphene oxide (GO), which decreases the Raman signal of GO.

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