scholarly journals Early stage release control of an anticancer drug by drug-polymer miscibility in a hydrophobic fiber-based drug delivery system

RSC Advances ◽  
2018 ◽  
Vol 8 (35) ◽  
pp. 19791-19803 ◽  
Author(s):  
Yue Yuan ◽  
Kyoungju Choi ◽  
Seong-O Choi ◽  
Jooyoun Kim

The drug release profiles of doxorubicin-loaded electrospun fiber mats were investigated with regard to drug-polymer miscibility, fiber wettability and degradability.

2015 ◽  
Vol 51 (45) ◽  
pp. 9343-9345 ◽  
Author(s):  
Soyeon Park ◽  
Eunjin Kim ◽  
Won Young Kim ◽  
Chulhun Kang ◽  
Jong Seung Kim

A novel biotin-guided anticancer drug delivery system, prodrug 9, consisting of biotin, nitrobenzene, and doxorubicin, with acid-triggered drug releasing capability was synthesized.


2015 ◽  
Vol 3 (17) ◽  
pp. 3490-3497 ◽  
Author(s):  
Shrabani Barman ◽  
Sourav K. Mukhopadhyay ◽  
Moumita Gangopadhyay ◽  
Sandipan Biswas ◽  
Satyahari Dey ◽  
...  

We have developed an ESIPT based drug delivery system, Cou–Benz–Cbl conjugate, with pH sensitive fluorescence properties and photocontrolled release of the anticancer drug chlorambucil.


RSC Advances ◽  
2017 ◽  
Vol 7 (84) ◽  
pp. 53401-53406 ◽  
Author(s):  
Ke Ma ◽  
Yiping Qiu ◽  
Yaqin Fu ◽  
Qing-Qing Ni

Six kinds of nanoscale application are designed in this study. A significant increase of drug release rate can be observed at the gastric site.


RSC Advances ◽  
2019 ◽  
Vol 9 (44) ◽  
pp. 25592-25601 ◽  
Author(s):  
Adhisankar Vadivelmurugan ◽  
Rajeshkumar Anbazhagan ◽  
Vinothini Arunagiri ◽  
Juin-Yih Lai ◽  
Hsieh-Chih Tsai

In this study, bio-responsive polymeric MoS2 nanocomposites were prepared for use as a drug carrier for cancer therapy.


2015 ◽  
Vol 3 (8) ◽  
pp. 1597-1604 ◽  
Author(s):  
Faheem Muhammad ◽  
Wenxiu Qi ◽  
Aifei Wang ◽  
Jingkai Gu ◽  
Jianshi Du ◽  
...  

Ultrasmall thiol passivated ZnS NPs are prepared using a newly developed synthetic protocol. Exposure to hydroxyl radicals results in oxidation of the thiol groups, thus destabilizing the ZnS nanolids to open drug encompassing pores for attaining an inflammation responsive drug delivery system.


2018 ◽  
Vol 6 (8) ◽  
pp. 1216-1225 ◽  
Author(s):  
Tao Zhang ◽  
Yongjia Tang ◽  
Wei Zhang ◽  
Shan Liu ◽  
Yumei Zhao ◽  
...  

A novel injectable and biodegradable cross-linked cyanoacrylate-based local drug delivery system with excellent anticancer activity.


Small ◽  
2014 ◽  
Vol 11 (8) ◽  
pp. 919-925 ◽  
Author(s):  
Guocan Yu ◽  
Wei Yu ◽  
Zhengwei Mao ◽  
Changyou Gao ◽  
Feihe Huang

RSC Advances ◽  
2019 ◽  
Vol 9 (72) ◽  
pp. 42395-42408 ◽  
Author(s):  
Rabindran Jermy Balasamy ◽  
Vijaya Ravinayagam ◽  
Munther Alomari ◽  
Mohammad Azam Ansari ◽  
Sarah Ameen Almofty ◽  
...  

The role of nano ZIF-8 in a Fe/SBA-16/ZIF composite has been explored as a potential anticancer drug and drug delivery system.


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