scholarly journals Pluronic F127 self-assembled MoS2 nanocomposites as an effective glutathione responsive anticancer drug delivery system

RSC Advances ◽  
2019 ◽  
Vol 9 (44) ◽  
pp. 25592-25601 ◽  
Author(s):  
Adhisankar Vadivelmurugan ◽  
Rajeshkumar Anbazhagan ◽  
Vinothini Arunagiri ◽  
Juin-Yih Lai ◽  
Hsieh-Chih Tsai
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Drug Carrier ◽  
Pluronic F127 ◽  
Anticancer Drug Delivery ◽  
System P ◽  
Self Assembled

In this study, bio-responsive polymeric MoS2 nanocomposites were prepared for use as a drug carrier for cancer therapy.

scholarly journals Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance

2015 ◽  
Vol 112 (10) ◽  
pp. 2978-2983 ◽  
Author(s):  
Tuo Wei ◽  
Chao Chen ◽  
Juan Liu ◽  
Cheng Liu ◽  
Paola Posocco ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Drug Carrier ◽  
Drug Loading ◽  
Cancer Drug ◽  
Self Assembling

Drug resistance and toxicity constitute challenging hurdles for cancer therapy. The application of nanotechnology for anticancer drug delivery is expected to address these issues and bring new hope for cancer treatment. In this context, we established an original nanomicellar drug delivery system based on an amphiphilic dendrimer (AmDM), which could generate supramolecular micelles to effectively encapsulate the anticancer drug doxorubicin (DOX) with high drug-loading capacity (>40%), thanks to the unique dendritic structure creating large void space for drug accommodation. The resulting AmDM/DOX nanomicelles were able to enhance drug potency and combat doxorubicin resistance in breast cancer models by significantly enhancing cellular uptake while considerably decreasing efflux of the drug. In addition, the AmDM/DOX nanoparticles abolished significantly the toxicity related to the free drug. Collectively, our studies demonstrate that the drug delivery system based on nanomicelles formed with the self-assembling amphiphilic dendrimer constitutes a promising and effective drug carrier in cancer therapy.

Development of Disulfide Core-Crosslinked Pluronic Nanoparticles as an Effective Anticancer-Drug-Delivery System

2011 ◽  
Vol 11 (9) ◽  
pp. 1264-1271 ◽  
Author(s):  
Abdullah-Al-Nahain ◽  
Haeshin Lee ◽  
Young Sun Lee ◽  
Kang Dae Lee ◽  
Sung Young Park
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Anticancer Drug Delivery

scholarly journals Green biosynthesis of superparamagnetic magnetite Fe3O4 nanoparticles and biomedical applications in targeted anticancer drug delivery system: A review

2020 ◽  
Vol 13 (1) ◽  
pp. 2287-2308 ◽  
Author(s):  
Yen Pin Yew ◽  
Kamyar Shameli ◽  
Mikio Miyake ◽  
Nurul Bahiyah Bt Ahmad Khairudin ◽  
Shaza Eva Bt Mohamad ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Fe3o4 Nanoparticles ◽  
Biomedical Applications ◽  
Anticancer Drug Delivery ◽  
System A ◽  
Magnetite Fe3o4

Electrospun polyacrylonitrile/cellulose acetate/MIL-125/TiO2 composite nanofibers as an efficient photocatalyst and anticancer drug delivery system

Cellulose ◽  
2020 ◽  
Vol 27 (17) ◽  
pp. 10029-10045
Author(s):  
Ehsan Bahmani ◽  
Hasti Seyyed Zonouzi ◽  
Shahnaz Koushkbaghi ◽  
Farnoosh Keyvani Hafshejani ◽  
Arash Fassadi Chimeh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cellulose Acetate ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Composite Nanofibers ◽  
Anticancer Drug Delivery
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