Homodimerization driven self-assembly of glycoluril molecular clips with covalently immobilized poly(ε-caprolactone)

The synthesis of a supramolecular double hydrophilic peptide polymer conjugate, held together by cucurbit[8]uril (CB[8]) ternary complexation, and its subsequent temperature triggered self assembly into vesicles are reported.

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Bipyridine functionalized molecular clips. Self-assembly of their ruthenium complexes in water

Chemical Communications ◽

10.1039/a803327g ◽

1998 ◽

pp. 1553-1554 ◽

Cited By ~ 25

Author(s):

Johannes A. A. W. Elemans ◽

Alan E. Rowan ◽

Roeland J. M. Nolte ◽

Johannes A. A. W. Elemans ◽

René de Gelder

Keyword(s):

Self Assembly ◽

Ruthenium Complexes ◽

Molecular Clips

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Effect of polymer chemistry on globular protein–polymer block copolymer self-assembly

Polymer Chemistry ◽

10.1039/c4py00448e ◽

2014 ◽

Vol 5 (17) ◽

pp. 4884-4895 ◽

Cited By ~ 31

Author(s):

Dongsook Chang ◽

Christopher N. Lam ◽

Shengchang Tang ◽

Bradley D. Olsen

Keyword(s):

Phase Transitions ◽

Block Copolymer ◽

Self Assembly ◽

Polymer Chemistry ◽

Protein Polymer ◽

Polymer Conjugate ◽

Cubic Phases ◽

Polymer Interactions ◽

Nanostructure Control ◽

Polymer Block

Changing polymer chemistry in protein–polymer conjugate block copolymers results in the formation of previously unobserved cubic phases and changes in protein–polymer interactions that create large shifts in phase transitions, providing a powerful tool for nanostructure control.

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Probing the Folding of Peptide–Polymer Conjugates Using the π-Dimerization of Viologen End-Groups

Organic Materials ◽

10.1055/s-0040-1710343 ◽

2020 ◽

Vol 02 (02) ◽

pp. 143-148

Author(s):

Ronja Otter ◽

Pol Besenius

Keyword(s):

Self Assembly ◽

Optical Probe ◽

Intermediate Structure ◽

Reduction Step ◽

Ph Responsive ◽

Polymer Conjugates ◽

Polymer Conjugate ◽

Hydrogel Matrix ◽

Close Proximity ◽

End Groups

The synthesis of a foldable viologen-functionalized peptide–polymer conjugate is presented. The ABA-type triblock conjugate with a PEG polymer was capped with a FHFHF pentapeptide sequence and further modified with a viologen building block at both chain ends. The pH-responsive peptide domains fold into an intermediate structure inducing close proximity of the viologen units, which upon a reduction step form π-dimers of the radical cation. Overall the intramolecular folding and intermolecular self-assembly process leads to the formation of supramolecular nanorods. Mixing of viologen-peptide–polymer conjugates with unfunctionalized conjugates leads to crosslinking of the nanorods and hydrogels with a tunable content of viologen end groups. π-Dimerization in the gels induces a deep purple color, which is used as an optical probe to monitor the diffusion of molecular oxygen through the hydrogel matrix.

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Dual Molecular Recognition Leading to a Protein–Polymer Conjugate and Further Self-Assembly

ACS Macro Letters ◽

10.1021/mz400036t ◽

2013 ◽

Vol 2 (3) ◽

pp. 278-283 ◽

Cited By ~ 41

Author(s):

Kongchang Wei ◽

Jun Li ◽

Guosong Chen ◽

Ming Jiang

Keyword(s):

Molecular Recognition ◽

Self Assembly ◽

Protein Polymer ◽

Polymer Conjugate

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In vitro and in vivo polysaccharides assembly: ultrastructural and cytochemical study of growing plant cell wall components.

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100083035 ◽

1978 ◽

Vol 36 (2) ◽

pp. 434-435

Author(s):

D. Reis ◽

B. Vian ◽

J. C. Roland

Keyword(s):

Cell Wall ◽

Self Assembly ◽

Plant Cell Wall ◽

Higher Plants ◽

Three Dimensional ◽

Cytochemical Study ◽

Wall Components

Wall morphogenesis in higher plants is a problem still open to controversy. Until now the possibility of a transmembrane control and the involvement of microtubules were mostly envisaged. Self-assembly processes have been observed in the case of walls of Chlamydomonas and bacteria. Spontaneous gelling interactions between xanthan and galactomannan from Ceratonia have been analyzed very recently. The present work provides indications that some processes of spontaneous aggregation could occur in higher plants during the formation and expansion of cell wall.Observations were performed on hypocotyl of mung bean (Phaseolus aureus) for which growth characteristics and wall composition have been previously defined.In situ, the walls of actively growing cells (primary walls) show an ordered three-dimensional organization (fig. 1). The wall is typically polylamellate with multifibrillar layers alternately transverse and longitudinal. Between these layers intermediate strata exist in which the orientation of microfibrils progressively rotates. Thus a progressive change in the morphogenetic activity occurs.

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The Nature of Rapidly Extracted Phycocyanin from the Blue-Green Alga Plectonema Boryanum

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100065870 ◽

1971 ◽

Vol 29 ◽

pp. 366-367

Author(s):

M. Kessel ◽

R. MacColl

Keyword(s):

Self Assembly ◽

Analytical Ultracentrifugation ◽

Uranyl Acetate ◽

The Self ◽

Major Protein ◽

Subunit Structure ◽

Blue Green Alga ◽

Thin Sections ◽

Blue Green Algae ◽

Cacodylate Buffer

The major protein of the blue-green algae is the biliprotein, C-phycocyanin (Amax = 620 nm), which is presumed to exist in the cell in the form of distinct aggregates called phycobilisomes. The self-assembly of C-phycocyanin from monomer to hexamer has been extensively studied, but the proposed next step in the assembly of a phycobilisome, the formation of 19s subunits, is completely unknown. We have used electron microscopy and analytical ultracentrifugation in combination with a method for rapid and gentle extraction of phycocyanin to study its subunit structure and assembly.To establish the existence of phycobilisomes, cells of P. boryanum in the log phase of growth, growing at a light intensity of 200 foot candles, were fixed in 2% glutaraldehyde in 0.1M cacodylate buffer, pH 7.0, for 3 hours at 4°C. The cells were post-fixed in 1% OsO4 in the same buffer overnight. Material was stained for 1 hour in uranyl acetate (1%), dehydrated and embedded in araldite and examined in thin sections.

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