Coupling strand extension/excision amplification with target recycling enables highly sensitive and aptamer-based label-free sensing of ATP in human serum

The Analyst ◽  
2020 ◽  
Vol 145 (2) ◽  
pp. 434-439 ◽  
Author(s):  
Lin Xu ◽  
Bingying Jiang ◽  
Wenjiao Zhou ◽  
Ruo Yuan ◽  
Yun Xiang
Keyword(s):  
Human Serum ◽  
Signal Enhancement ◽  
Label Free ◽  
Target Recycling ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Recycling Amplification

The integration of strand extension and excision recycling amplification leads to substantial signal enhancement for highly sensitive and label-free detection of ATP.

Target-induced structure switching of DNA for label-free and ultrasensitive electrochemiluminescent detection of proteins

2014 ◽  
Vol 50 (24) ◽  
pp. 3211-3213 ◽  
Author(s):  
Mengli Yang ◽  
Ying Chen ◽  
Yun Xiang ◽  
Ruo Yuan ◽  
Yaqin Chai
Keyword(s):  
Dna Structure ◽  
Label Free ◽  
Switching Strategy ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Exo Iii ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Highly sensitive and label-free detection of thrombin is achieved via a target-induced DNA structure switching strategy and Exo III-assisted recycling amplification.

Label-free detection of Cu(ii) in a human serum sample by using a prion protein-immobilized FET sensor

The Analyst ◽  
2015 ◽  
Vol 140 (19) ◽  
pp. 6485-6488 ◽  
Author(s):  
Shofarul Wustoni ◽  
Sho Hideshima ◽  
Shigeki Kuroiwa ◽  
Takuya Nakanishi ◽  
Yasuro Mori ◽  
...  
Keyword(s):  
Human Serum ◽  
Prion Protein ◽  
Serum Sample ◽  
Prion Proteins ◽  
Human Serum Sample ◽  
Label Free ◽  
Highly Sensitive ◽  
Label Free Detection

We report a simple and label-free detection of Cu2+utilizing prion proteins as the recognition molecules, which can provide highly sensitive and selective performance at the nanomolar level in a human serum sample.

A multi-recycling amplification-based sensor for label-free and highly sensitive detection of telomerase from cancer cells

2019 ◽  
Vol 1086 ◽  
pp. 116-121 ◽  
Author(s):  
Xiaoxia Liu ◽  
Xia Li ◽  
Jin Li ◽  
Bingying Jiang ◽  
Ruo Yuan ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Sensitive Detection ◽  
Label Free ◽  
Highly Sensitive ◽  
Recycling Amplification ◽  
Highly Sensitive Detection

Label-free DNA detection based on oligonucleotide-stabilized silver nanoclusters and exonuclease III-catalyzed target recycling amplification

2014 ◽  
Vol 6 (15) ◽  
pp. 6082-6087 ◽  
Author(s):  
Hui Ma ◽  
Wei Wei ◽  
Qian Lu ◽  
Zhixin Zhou ◽  
Henan Li ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Silver Nanoclusters ◽  
Label Free ◽  
Exonuclease Iii ◽  
Target Recycling ◽  
Free Dna ◽  
Sensitivity And Selectivity ◽  
Exo Iii ◽  
Ag Ncs ◽  
Recycling Amplification

A label-free DNA biosensor with high sensitivity and selectivity is constructed by using DNA–Ag NCs and Exo III-catalyzed target recycling amplification.

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