Target-induced structure switching of DNA for label-free and ultrasensitive electrochemiluminescent detection of proteins

2014 ◽  
Vol 50 (24) ◽  
pp. 3211-3213 ◽  
Author(s):  
Mengli Yang ◽  
Ying Chen ◽  
Yun Xiang ◽  
Ruo Yuan ◽  
Yaqin Chai
Keyword(s):  
Dna Structure ◽  
Label Free ◽  
Switching Strategy ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Exo Iii ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Highly sensitive and label-free detection of thrombin is achieved via a target-induced DNA structure switching strategy and Exo III-assisted recycling amplification.

Coupling strand extension/excision amplification with target recycling enables highly sensitive and aptamer-based label-free sensing of ATP in human serum

The Analyst ◽  
2020 ◽  
Vol 145 (2) ◽  
pp. 434-439 ◽  
Author(s):  
Lin Xu ◽  
Bingying Jiang ◽  
Wenjiao Zhou ◽  
Ruo Yuan ◽  
Yun Xiang
Keyword(s):  
Human Serum ◽  
Signal Enhancement ◽  
Label Free ◽  
Target Recycling ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Recycling Amplification

The integration of strand extension and excision recycling amplification leads to substantial signal enhancement for highly sensitive and label-free detection of ATP.

Label-free DNA detection based on oligonucleotide-stabilized silver nanoclusters and exonuclease III-catalyzed target recycling amplification

2014 ◽  
Vol 6 (15) ◽  
pp. 6082-6087 ◽  
Author(s):  
Hui Ma ◽  
Wei Wei ◽  
Qian Lu ◽  
Zhixin Zhou ◽  
Henan Li ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Silver Nanoclusters ◽  
Label Free ◽  
Exonuclease Iii ◽  
Target Recycling ◽  
Free Dna ◽  
Sensitivity And Selectivity ◽  
Exo Iii ◽  
Ag Ncs ◽  
Recycling Amplification

A label-free DNA biosensor with high sensitivity and selectivity is constructed by using DNA–Ag NCs and Exo III-catalyzed target recycling amplification.

Target-induced structure switching of aptamers facilitates strand displacement for DNAzyme recycling amplification detection of thrombin in human serum

The Analyst ◽  
2019 ◽  
Vol 144 (7) ◽  
pp. 2430-2435 ◽  
Author(s):  
Jin Li ◽  
Sujing Wang ◽  
Bingying Jiang ◽  
Yun Xiang ◽  
Ruo Yuan
Keyword(s):  
Human Serum ◽  
Strand Displacement ◽  
Recycling Amplification ◽  
Structure Switching ◽  
Induced Structure

Target-induced sequence proximity leads to strand displacement formation of DNAzymes for amplified detection of thrombin in human serum.

A novel label-free fluorescent molecular beacon for the detection of 3′–5′ exonuclease enzymatic activity using DNA-templated copper nanoclusters

2017 ◽  
Vol 41 (18) ◽  
pp. 9718-9723 ◽  
Author(s):  
Jia Ge ◽  
Zhen-Zhen Dong ◽  
Dong-Mei Bai ◽  
Lin Zhang ◽  
Ya-Lei Hu ◽  
...  
Keyword(s):  
Enzymatic Activity ◽  
Molecular Beacon ◽  
Label Free ◽  
Copper Nanoclusters ◽  
Selective Determination ◽  
Highly Sensitive ◽  
Exo Iii

A label-free biosensor was developed for highly sensitive and selective determination of Exo III based on poly(T) molecular beacon-templated CuNPs.

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