Target Recycling Transcription of Lighting-Up RNA Aptamers for Highly Sensitive and Label-Free Detection of ATP

Author(s):  
Jia Lun He ◽  
Bing Ying Jiang ◽  
Wen Jiao Zhou ◽  
Ruo Yuan ◽  
Yun Xiang
The Analyst ◽  
2020 ◽  
Vol 145 (2) ◽  
pp. 434-439 ◽  
Author(s):  
Lin Xu ◽  
Bingying Jiang ◽  
Wenjiao Zhou ◽  
Ruo Yuan ◽  
Yun Xiang

The integration of strand extension and excision recycling amplification leads to substantial signal enhancement for highly sensitive and label-free detection of ATP.


2014 ◽  
Vol 50 (24) ◽  
pp. 3211-3213 ◽  
Author(s):  
Mengli Yang ◽  
Ying Chen ◽  
Yun Xiang ◽  
Ruo Yuan ◽  
Yaqin Chai

Highly sensitive and label-free detection of thrombin is achieved via a target-induced DNA structure switching strategy and Exo III-assisted recycling amplification.


Biosensors ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 120 ◽  
Author(s):  
Vladimir Bochenkov ◽  
Tatyana Shabatina

Biosensing requires fast, selective, and highly sensitive real-time detection of biomolecules using efficient simple-to-use techniques. Due to a unique capability to focus light at nanoscale, plasmonic nanostructures provide an excellent platform for label-free detection of molecular adsorption by sensing tiny changes in the local refractive index or by enhancing the light-induced processes in adjacent biomolecules. This review discusses the opportunities provided by surface plasmon resonance in probing the chirality of biomolecules as well as their conformations and orientations. Various types of chiral plasmonic nanostructures and the most recent developments in the field of chiral plasmonics related to biosensing are considered.


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