Engineering DNAzyme cascade for signal transduction and amplification

The Analyst ◽  
2020 ◽  
Vol 145 (5) ◽  
pp. 1925-1932 ◽  
Author(s):  
Jing Li ◽  
Ke Quan ◽  
Yanjing Yang ◽  
Xiaohai Yang ◽  
Xiangxian Meng ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Signal Amplification ◽  
Cascade Reaction ◽  
Enzyme Cascade ◽  
Natural Enzyme ◽  
Intracellular Process

Inspired by the natural enzyme cascade reaction, a multiple DNAzyme cascade platform is engineered to imitate the intracellular process of signal transduction and signal amplification.

A DNAzyme cascade for amplified detection of intracellular miRNA

2020 ◽  
Vol 56 (70) ◽  
pp. 10163-10166
Author(s):  
Yanan Wu ◽  
Jing Li ◽  
Ke Quan ◽  
Xiangxian Meng ◽  
Xiaohai Yang ◽  
...  
Keyword(s):  
Cascade Reaction ◽  
Cascade System ◽  
Enzyme Cascade ◽  
Natural Enzyme

Inspired by the natural enzyme cascade reaction, an artificial DNAzyme cascade system is developed for the amplified detection of intracellular miR-141.

Dual-Mode Sensing of Biomarkers by Mimic Enzyme-Natural Enzyme Cascade Signal Amplification

2020 ◽  
Vol 78 (5) ◽  
pp. 419
Author(s):  
Lei Fan ◽  
Qunying Jiang ◽  
Min Pan ◽  
Wenxiao Wang ◽  
Li Zhang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Dual Mode ◽  
Enzyme Cascade ◽  
Natural Enzyme

Efficient biotransformation and synergetic mechanism of dual-enzyme cascade reaction in nonreducing maltoheptaose synthesis

2021 ◽  
pp. 101066
Author(s):  
Luhua Zheng ◽  
Bo Jiang ◽  
Jingjing Chen ◽  
Tao Zhang ◽  
Xiaohong Gu ◽  
...  
Keyword(s):  
Cascade Reaction ◽  
Enzyme Cascade
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