Vacuum-assisted electrokinetic supercharging in flow-gated capillary electrophoresis for rapid analysis of high-salt cerebrospinal fluid samples

2020 ◽  
Vol 12 (1) ◽  
pp. 25-32
Author(s):  
Naveen Maddukuri ◽  
Maojun Gong
Keyword(s):  
Cerebrospinal Fluid ◽  
Capillary Electrophoresis ◽  
Rapid Analysis ◽  
High Salt ◽  
Sample Concentration ◽  
Electrokinetic Supercharging

Vacuum-assisted electrokinetic supercharging was used to preconcentrate high-salt cerebrospinal fluid samples. A shows the procedure; B shows a typical voltage configuration; and C demonstrates the imaging evidence of the sample concentration.

Capillary electrophoresis of anions at high salt concentrations

1998 ◽  
Vol 19 (12) ◽  
pp. 2133-2139 ◽  
Author(s):  
Weiliang Ding ◽  
Michelle J. Thornton ◽  
James S. Fritz
Keyword(s):  
Capillary Electrophoresis ◽  
High Salt

scholarly journals Clinical Analysis by Microchip Capillary Electrophoresis

2006 ◽  
Vol 52 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Sam FY Li ◽  
Larry J Kricka
Keyword(s):  
Capillary Electrophoresis ◽  
High Throughput ◽  
Early Stage ◽  
Clinical Analysis ◽  
Rapid Analysis ◽  
Clinical Testing ◽  
Parallel Operation ◽  
Microchip Capillary Electrophoresis ◽  
Stage Of Development ◽  
Easy Integration

Abstract Clinical analysis often requires rapid, automated, and high-throughput analytical systems. Microchip capillary electrophoresis (CE) has the potential to achieve very rapid analysis (typically seconds), easy integration of multiple analytical steps, and parallel operation. Although it is currently still in an early stage of development, there are already many reports in the literature describing the applications of microchip CE in clinical analysis. At the same time, more fully automated and higher throughput commercial instruments for microchip CE are becoming available and are expected to further enhance the development of applications of microchip CE in routine clinical testing. To put into perspective its potential, we briefly compare microchip CE with conventional CE and review developments in this technique that may be useful in diagnosis of major diseases.

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