Nickel-catalyzed carbodifunctionalization of N-vinylamides enables access to γ-amino acids
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A nickel-catalyzed tandem reaction of N-vinylamides with arylboronic acids and bromodifluoroacetate has been developed. The reaction efficiently furnishes a series of protected α,α-difluoro-γ-amino acid esters.
1965 ◽
Vol 13
(8)
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pp. 995-1000
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1989 ◽
Vol 54
(18)
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pp. 4302-4313
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2010 ◽
Vol 92
(8)
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pp. 819-825
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1975 ◽
Vol 23
(7)
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pp. 1608-1611
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1971 ◽
Vol 26
(8)
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pp. 762-764
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