Supramolecular polymer nanocapsules by enzymatic covalent condensation: biocompatible and biodegradable drug-delivery systems for chemo-photothermal anticancer therapy

2019 ◽  
Vol 10 (26) ◽  
pp. 3566-3570 ◽  
Author(s):  
Shengda Liu ◽  
Zupeng Huang ◽  
Fei Li ◽  
Tengfei Yan ◽  
Shuang Fu ◽  
...  

Supramolecular polymer nanocapsules were constructed by enzymatic covalent condensation and they acted as drug-delivery systems for chemo-photothermal anticancer therapy.

2016 ◽  
Vol 7 (4) ◽  
pp. 887-898 ◽  
Author(s):  
Stefano Stefani ◽  
Indah N. Kurniasih ◽  
Sunil K. Sharma ◽  
Christoph Böttcher ◽  
Paul Servin ◽  
...  

A set of biodegradable nanocarriers characterized by a hyperbranched polyester core and an amphiphilic branched shell was developed and employed to efficiently solubilize hydrophobic drugs in aqueous media.


2006 ◽  
Vol 17 (2) ◽  
pp. 302-313 ◽  
Author(s):  
Mohamed Al Malyan ◽  
Chiara Becchi ◽  
Lila Nikkola ◽  
Petrus Viitanen ◽  
Sergio Boncinelli ◽  
...  

Author(s):  
Harshita Abul Barkat ◽  
Md Abul Barkat ◽  
Mohamad Taleuzzaman ◽  
Sabya Sachi Das ◽  
Md. Rizwanullah ◽  
...  

Nanotechnology-based drug-delivery systems, as an anticancer therapy tool, have shown significant potentials for the diagnosis and treatment of cancer. Recent studies have demonstrated that cancer therapy could be efficiently achieved by combinatorial therapies, approaches using multiple drug regimens for targeting cancers. However, their usages have been limited due to shorter half-lives of chemotherapeutic agents, insignificant targetability to tumor sites and suboptimal levels of co-administered conventional drug moieties. Thus, nanotechnology-based drug-delivery systems with effective targetability have played a crucial role to overcome the limitations and challenges associated with conventional therapies and also have provided greater therapeutic efficacy. Herein, the authors have focused on various drug-incorporated combinatorial nanocarrier systems, the significance of various receptors-associated strategies, and various targeted delivery approaches for chemotherapeutic agents.


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