scholarly journals Linear and nonlinear mechanical responses can be quite different in models for biological tissues

Soft Matter ◽  
2020 ◽  
Vol 16 (7) ◽  
pp. 1850-1856 ◽  
Author(s):  
Preeti Sahu ◽  
Janice Kang ◽  
Gonca Erdemci-Tandogan ◽  
M. Lisa Manning
Keyword(s):  
Biological Tissues ◽  
Mechanical Responses ◽  
Nonlinear Mechanical ◽  
Linear And Nonlinear

The fluidity of biological tissues – whether cells can change neighbors and rearrange – is important for their function.

Nonlinear Mechanical Responses of Concrete Beams Reinforced with High-Performance CFRP Tendons

2021 ◽  
Author(s):  
J. Zhang ◽  
Y. L. Jiang ◽  
H. Liu ◽  
X. M. Zhao ◽  
X. Chen ◽  
...  
Keyword(s):  
High Performance ◽  
Concrete Beams ◽  
Mechanical Responses ◽  
Nonlinear Mechanical

Effect of Filler Morphology and Distribution State on the Linear and Nonlinear Mechanical Behavior of Nanofilled Elastomers

2017 ◽  
Vol 50 (17) ◽  
pp. 6369-6384 ◽  
Author(s):  
Mathieu Tauban ◽  
Jean-Yves Delannoy ◽  
Paul Sotta ◽  
Didier R. Long
Keyword(s):  
Mechanical Behavior ◽  
Nonlinear Mechanical ◽  
Linear And Nonlinear ◽  
Distribution State

Mechanics of the human femoral adventitia including the high-pressure response

2002 ◽  
Vol 282 (6) ◽  
pp. H2427-H2440 ◽  
Author(s):  
Christian A. J. Schulze-Bauer ◽  
Peter Regitnig ◽  
Gerhard A. Holzapfel
Keyword(s):  
High Pressures ◽  
Energy Functions ◽  
Mean Values ◽  
Mechanical Responses ◽  
Strongly Nonlinear ◽  
Pressure Load ◽  
Nonlinear Mechanical ◽  
Load Carrying

Adventitial mechanics were studied on the basis of adventitial tube tests and associated stress analyses utilizing a thin-walled model. Inflation tests of 11 nonstenotic human femoral arteries (79.3 ± 8.2 yr, means ± SD) were performed during autopsy. Adventitial tubes were separated anatomically and underwent cyclic, quasistatic extension-inflation tests using physiological pressures and high pressures up to 100 kPa. Associated circumferential and axial stretches were typically <20%, indicating “adventitiosclerosis.” Adventitias behaved nearly elastically for both loading domains, demonstrating high tensile strengths (>1 MPa). The anisotropic and strongly nonlinear mechanical responses were represented appropriately by two-dimensional Fung-type stored-energy functions. At physiological pressure (13.3 kPa), adventitias carry ∼25% of the pressure load in situ, whereas their circumferential and axial stresses were similar to the total wall stresses (∼50 kPa in both directions), supporting a “uniform stress hypothesis.” At higher pressures, they became the mechanically predominant layer, carrying >50% of the pressure load. These significant load-carrying capabilities depended strongly on circumferential and axial in-vessel prestretches (mean values: 0.95 and 1.08). On the basis of these results, the mechanical role of the adventitia at physiological and hypertensive states and during balloon angioplasty was characterized.

BIOMECHANICAL CHARACTERIZATION OF NORMAL AND PROLAPSED VAGINAL TISSUE SURROGATES

2018 ◽  
Vol 18 (03) ◽  
pp. 1750100 ◽  
Author(s):  
ARNAB CHANDA ◽  
ZACHARY FLYNN ◽  
VINU UNNIKRISHNAN
Keyword(s):  
Mechanical Behavior ◽  
Experimental Testing ◽  
Low Cost ◽  
Vaginal Tissue ◽  
Novel Materials ◽  
Tissue Interactions ◽  
Surgical Suture ◽  
Nonlinear Mechanical ◽  
Implantation Techniques ◽  
Linear And Nonlinear

In the recent years, poorly evaluated gynecological surgeries and urogynecological mesh implantations have been affecting millions of women in the US and across the globe. These failed surgeries could be mainly attributed to the nonavailability of vaginal tissues (due to ethical and biosafety issues), which does not allow any experimental testing of operation and mesh implantation techniques before an actual surgery. A surrogate which behaves biomechanically like the human vaginal tissue would be indispensable for simulating surgical suture of vaginal tissues in prolapse surgery, hysterectomy or surgery during traumatic child births (such as Cesarean). Also, vaginal tissue surrogates simulating the various prolapse conditions (such as vaginal tissue stiffening) would be very useful to evaluate tissue modifications due to prolapse, and also mesh and vaginal tissue interactions. In the current work, a low cost four-part silicone-based material was developed, which precisely simulates the linear and nonlinear mechanical behavior of the normal human vaginal tissue. Additionally, a range of four-part silicone-based novel materials were developed which precisely mimics the mechanical behavior of stiffened vaginal tissues at different degrees of prolapse. The linear and nonlinear mechanical behavior of all such novel materials were characterized using elastic and hyperelastic formulations. Such precisely characterized normal and prolapsed vaginal tissue surrogates have not been developed anywhere to date as per the best of our knowledge and would be clinically helpful for gynecological surgical planning in the future.

Linear and nonlinear microrheology of lysozyme layers forming at the air–water interface

Soft Matter ◽  
2014 ◽  
Vol 10 (36) ◽  
pp. 7051-7060 ◽  
Author(s):  
Daniel B. Allan ◽  
Daniel M. Firester ◽  
Victor P. Allard ◽  
Daniel H. Reich ◽  
Kathleen J. Stebe ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Water Interface ◽  
Nonlinear Mechanical ◽  
Air Water Interface ◽  
Linear And Nonlinear

Microrheology tracks the evolution in the linear and nonlinear mechanical properties of layers of the protein lysozyme adsorbing at the air–water interface as the layers undergo a viscoelastic transition.

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