Label-free and amplified detection of apoptosis-associated caspase activity using branched rolling circle amplification

2020 ◽  
Vol 56 (39) ◽  
pp. 5243-5246
Author(s):  
Meng Liu ◽  
Di Zhang ◽  
Xuechong Zhang ◽  
Qinfeng Xu ◽  
Fei Ma ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Fluorescence Method ◽  
Ultrasensitive Detection ◽  
Caspase Activity ◽  
Label Free ◽  
Rolling Circle

We develop a label-free fluorescence method for ultrasensitive detection of apoptosis-associated caspase activity based on branched rolling circle amplification.

Sensitive and label-free discrimination of 5-hydroxymethylcytosine and 5-methylcytosine in DNA by ligation-mediated rolling circle amplification

2018 ◽  
Vol 54 (62) ◽  
pp. 8602-8605 ◽  
Author(s):  
Zi-yue Wang ◽  
Meng Wang ◽  
Yan Zhang ◽  
Chun-yang Zhang
Keyword(s):  
Rolling Circle Amplification ◽  
Fluorescence Method ◽  
Label Free ◽  
Rolling Circle

We develop a label-free fluorescence method for sensitive discrimination of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) by ligation-mediated rolling circle amplification.

Target-responsive dumbbell probe-mediated rolling circle amplification strategy for highly sensitive Hg2+ detection

RSC Advances ◽  
2014 ◽  
Vol 4 (51) ◽  
pp. 27091-27097 ◽  
Author(s):  
Qingwang Xue ◽  
Yanqin Lv ◽  
Yuanfu Zhang ◽  
Shuling Xu ◽  
Qiaoli Yue ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Selective Detection ◽  
Label Free ◽  
Rolling Circle ◽  
Fluorescent Sensing ◽  
Highly Sensitive ◽  
Mercuric Ions ◽  
Amplification Strategy

A novel label-free amplified fluorescent sensing scheme based on target-responsive dumbbell probe-mediated rolling circle amplification (D-RCA) has been developed for sensitive and selective detection of mercuric ions.

Ultrasensitive detection of lung cancer-associated miRNAs by multiple primer-mediated rolling circle amplification coupled with a graphene oxide fluorescence-based (MPRCA-GO) sensor

The Analyst ◽  
2019 ◽  
Vol 144 (14) ◽  
pp. 4180-4187 ◽  
Author(s):  
Krissana Khoothiam ◽  
Kiatnida Treerattrakoon ◽  
Tawin Iempridee ◽  
Patraporn Luksirikul ◽  
Tararaj Dharakul ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Graphene Oxide ◽  
Cancer Diagnosis ◽  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

MPRCA-GO sensor can detect low amount of miRNAs, which are biomarkers in cancer diagnosis.

A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rolling circle amplification

2010 ◽  
Vol 46 (36) ◽  
pp. 6720 ◽  
Author(s):  
Wei Cheng ◽  
Lin Ding ◽  
Yunlong Chen ◽  
Feng Yan ◽  
Huangxian Ju ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle
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