Ultrasensitive detection of lung cancer-associated miRNAs by multiple primer-mediated rolling circle amplification coupled with a graphene oxide fluorescence-based (MPRCA-GO) sensor

The Analyst ◽  
2019 ◽  
Vol 144 (14) ◽  
pp. 4180-4187 ◽  
Author(s):  
Krissana Khoothiam ◽  
Kiatnida Treerattrakoon ◽  
Tawin Iempridee ◽  
Patraporn Luksirikul ◽  
Tararaj Dharakul ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Graphene Oxide ◽  
Cancer Diagnosis ◽  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

MPRCA-GO sensor can detect low amount of miRNAs, which are biomarkers in cancer diagnosis.

A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rolling circle amplification

2010 ◽  
Vol 46 (36) ◽  
pp. 6720 ◽  
Author(s):  
Wei Cheng ◽  
Lin Ding ◽  
Yunlong Chen ◽  
Feng Yan ◽  
Huangxian Ju ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

Ultrasensitive detection of T-2 toxin in food based on bio-barcode and rolling circle amplification

2018 ◽  
Vol 1043 ◽  
pp. 98-106 ◽  
Author(s):  
Man Zhang ◽  
Bingyang Huo ◽  
Shuai Yuan ◽  
Baoan Ning ◽  
Jialei Bai ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Ultrasensitive Detection ◽  
Rolling Circle

A fluorescent biosensor for highly specific and ultrasensitive detection of adenosine triphosphate based on ligation-triggered branched rolling circle amplification

2019 ◽  
Vol 11 (36) ◽  
pp. 4629-4636
Author(s):  
Hongxin Jiang ◽  
Guimei Han ◽  
Yaping Xu ◽  
Junxing Li ◽  
Xiaowei Liu ◽  
...  
Keyword(s):  
Adenosine Triphosphate ◽  
Rolling Circle Amplification ◽  
Dna Ligase ◽  
Ultrasensitive Detection ◽  
Selective Detection ◽  
Rolling Circle ◽  
T4 Dna Ligase ◽  
Fluorescent Sensing ◽  
Fluorescent Biosensor

A fluorescent sensing strategy for ultrasensitive and highly selective detection of ATP was presented by taking advantage of the exponential amplification capability of BRCA and the extreme specificity of T4 DNA ligase toward ATP.

Aptamer-based rolling circle amplification coupled with graphene oxide-based fluorescence resonance energy transfer for sensitive detection of cardiac troponin I

2018 ◽  
Vol 10 (15) ◽  
pp. 1767-1773 ◽  
Author(s):  
Yu Li ◽  
Weiqiang Dai ◽  
Xuefei Lv ◽  
Yulin Deng
Keyword(s):  
Graphene Oxide ◽  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Troponin I ◽  
Rolling Circle Amplification ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Protein Detection ◽  
Rolling Circle ◽  
Fluorescence Resonance

Combining the high affinity and specificity of an aptamer for a protein, a highly sensitive strategy for protein detection was developed based on rolling circle amplification (RCA) and graphene oxide based fluorescence resonance energy transfer (FRET).

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