An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence imaging

Junjie Chen; Yichang Fang; Lihe Sun; Fang Zeng; Shuizhu Wu

doi:10.1039/d0cc04635c

An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence imaging

Chemical Communications ◽

10.1039/d0cc04635c ◽

2020 ◽

Vol 56 (75) ◽

pp. 11102-11105

Author(s):

Junjie Chen ◽

Yichang Fang ◽

Lihe Sun ◽

Fang Zeng ◽

Shuizhu Wu

Keyword(s):

Cytochrome P450 ◽

Liver Injury ◽

Fluorescence Imaging ◽

Alcoholic Liver Injury ◽

Optoacoustic Tomography ◽

Activatable Probe

An activatable probe has been developed for imaging alcoholic liver injury through detecting the overexpressed cytochrome p450 (cyp450) reductase in hypoxia in the hepatic region.

Diagnosing Drug-Induced Liver Injury by Multispectral Optoacoustic Tomography and Fluorescence Imaging Using a Leucine-Aminopeptidase-Activated Probe

Analytical Chemistry ◽

10.1021/acs.analchem.9b00107 ◽

2019 ◽

Vol 91 (13) ◽

pp. 8085-8092 ◽

Cited By ~ 10

Author(s):

Yong Huang ◽

Yu Qi ◽

Chenyue Zhan ◽

Fang Zeng ◽

Shuizhu Wu

Keyword(s):

Liver Injury ◽

Fluorescence Imaging ◽

Leucine Aminopeptidase ◽

Drug Induced ◽

Drug Induced Liver Injury ◽

Optoacoustic Tomography

Dynamic evaluation of the protective effect of Dendrobium officinale polysaccharide on acute alcoholic liver injury mice in vitro and in vivo by NIR fluorescence imaging

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-021-03546-7 ◽

2021 ◽

Author(s):

Gang Nie ◽

Yu Zhang ◽

Zhihong Zhou ◽

Jingya Xu ◽

Huiling Wang ◽

...

Keyword(s):

Liver Injury ◽

Protective Effect ◽

Fluorescence Imaging ◽

Dendrobium Officinale ◽

Alcoholic Liver Injury ◽

Dynamic Evaluation ◽

Nir Fluorescence

An Activatable Probe with Aggregation‐Induced Emission for Detecting and Imaging Herbal Medicine Induced Liver Injury with Optoacoustic Imaging and NIR‐II Fluorescence Imaging

Advanced Healthcare Materials ◽

10.1002/adhm.202100867 ◽

2021 ◽

pp. 2100867

Author(s):

Lihe Sun ◽

Juan Ouyang ◽

Yunqing Ma ◽

Zhuo Zeng ◽

Cheng Zeng ◽

...

Keyword(s):

Herbal Medicine ◽

Liver Injury ◽

Fluorescence Imaging ◽

Optoacoustic Imaging ◽

Aggregation Induced Emission ◽

Activatable Probe

Faculty Opinions recommendation of The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727650646.793534215 ◽

2017 ◽

Author(s):

Pradeep Kumar

Keyword(s):

Liver Injury ◽

Hepatic Stellate Cells ◽

Stellate Cells ◽

Alcoholic Liver Injury

Human ESC-derived Expandable Hepatic Organoids Enable Therapeutic Liver Repopulation and Pathophysiological Modeling of Alcoholic Liver Injury

HPB ◽

10.1016/j.hpb.2020.11.110 ◽

2021 ◽

Vol 23 ◽

pp. S46

Author(s):

Y. Wang ◽

X. Wang

Keyword(s):

Liver Injury ◽

Alcoholic Liver Injury ◽

Liver Repopulation

Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish

Journal of Visualized Experiments ◽

10.3791/55630 ◽

2017 ◽

Cited By ~ 5

Author(s):

Jillian L. Ellis ◽

Chunyue Yin

Keyword(s):

Liver Injury ◽

Alcoholic Liver Injury

Effect of Lactobacillus casei on lipid metabolism and intestinal microflora in patients with alcoholic liver injury

European Journal of Clinical Nutrition ◽

10.1038/s41430-020-00852-8 ◽

2021 ◽

Author(s):

Xuelong Li ◽

Ying Liu ◽

Xiaofei Guo ◽

Yan Ma ◽

Huaqi Zhang ◽

...

Keyword(s):

Lipid Metabolism ◽

Liver Injury ◽

Lactobacillus Casei ◽

Intestinal Microflora ◽

Alcoholic Liver Injury

Echinacea purpurea polysaccharide prepared by fractional precipitation prevents alcoholic liver injury in mice by protecting the intestinal barrier and regulating liver-related pathways

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2021.07.095 ◽

2021 ◽

Author(s):

Wenhao Jiang ◽

Hongkang Zhu ◽

Wenqian Xu ◽

Chang Liu ◽

Bin Hu ◽

...

Keyword(s):

Liver Injury ◽

Intestinal Barrier ◽

Echinacea Purpurea ◽

Alcoholic Liver Injury ◽

Fractional Precipitation

Methionine metabolic pathway in alcoholic liver injury

Current Opinion in Clinical Nutrition & Metabolic Care ◽

10.1097/mco.0b013e32835a892a ◽

2013 ◽

Vol 16 (1) ◽

pp. 89-95 ◽

Cited By ~ 29

Author(s):

Kusum K. Kharbanda

Keyword(s):

Liver Injury ◽

Metabolic Pathway ◽

Alcoholic Liver Injury

The ameliorative effects of probiotic‐fermented soymilk on acute alcoholic liver injury

Journal of Food Processing and Preservation ◽

10.1111/jfpp.16026 ◽

2021 ◽

Author(s):

Yu Wang ◽

Haiyue Sun ◽

Yiying Chen ◽

Wuyang Guan ◽

Jun Zhang ◽

...

Keyword(s):

Liver Injury ◽

Alcoholic Liver Injury