Chemical profiling, antiviral and antiproliferative activities of the essential oil of Phlomis aurea Decne

2021 ◽  
Author(s):  
Zeinab Torky ◽  
Ashaimaa Yehia Mohammed Mohammed Moussa ◽  
Eman Abd El-Ghffar ◽  
Usama Abdel-Hameed ◽  
Omayma Eldahshan

Here, we investigated the chemical composition of the edible Phlomis aurea oil and its anticancer potential on four human cancer cell lines, as well as its antiviral activity against Herpes...

2011 ◽  
Vol 66 (3-4) ◽  
pp. 143-148 ◽  
Author(s):  
Hossam M. Abdallah ◽  
Shahira M. Ezzat

The aerial parts of Pituranthos tortuosus (Desf.) Benth and Hook (Apiaceae), growing wild in Egypt, yielded 0.8%, 0.6%, and 1.5% (v/w) of essential oil when prepared by hydrodistillation (HD), simultaneous hydrodistillation-solvent (n-pentane) extraction (Lickens- Nickerson, DE), and conventional volatile solvent extraction (preparation of the “absolute”, SE), respectively. GC-MS analysis showed that the major components in the HD sample were β-myrcene (18.81%), sabinene (18.49%), trans-iso-elemicin (12.90%), and terpinen- 4-ol (8.09%); those predominent in the DE sample were terpinen-4-ol (29.65%), sabinene (7.38%), γ-terpinene (7.27%), and β-myrcene (5.53%); while the prominent ones in the SE sample were terpinen-4-ol (15.40%), dill apiol (7.90%), and allo-ocimene (4E,6Z) (6.00%). The oil prepared in each case was tested for its cytotoxic activity on three human cancer cell lines, i.e. liver cancer cell line (HEPG2), colon cancer cell line (HCT116), and breast cancer cell line (MCF7). The DE sample showed the most potent activity against the three human cancer cell lines (with IC50 values of 1.67, 1.34, and 3.38 μg/ml against the liver, colon, and breast cancer cell lines, respectively). Terpinen-4-ol, sabinene, γ-terpinene, and β-myrcene were isolated from the DE sample and subjected to a similar evaluation of cytotoxic potency; signifi cant activity was observed


2006 ◽  
Vol 9 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Changqing Wu ◽  
Feng Chen ◽  
James W. Rushing ◽  
Xi Wang ◽  
Hyun-Jin Kim ◽  
...  

2012 ◽  
Vol 9 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Joanna Matysiak ◽  
Monika M. Karpińska ◽  
Andrzej Niewiadomy ◽  
Joanna Wietrzyk ◽  
Dagmara Kłopotowska

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