Semi-synthesis as a tool for broadening the health applications of bioactive olive secoiridoids: a critical review

2021 ◽  
Author(s):  
Manuela Oliverio ◽  
Monica Nardi ◽  
Maria Luisa Di Gioia ◽  
Paola Costanzo ◽  
Sonia Bonacci ◽  
...  

Semi-synthesis is an effective strategy to obtain both natural and synthetic analogues of the olive secoiridoids, starting from easy accessible natural compounds.

1963 ◽  
Vol 43 (4) ◽  
pp. 561-570 ◽  
Author(s):  
Gösta Bengtsson ◽  
Sven Ullberg

ABSTRACT The distribution in mice of 14C- and 3H-diethylstilboestrol has been investigated autoradiographically. The results have been compared with those which have been previously reported for natural oestrogens. Many similarities have been demonstrated between the synthetic and natural compounds. Thus a specific accumulation has been observed in the endometrium, the granulosa layer of large ovarian follicles, the adrenal cortex. the interstitial tissue of the testes, and the hypophysis. Natural and synthetic oestrogens differ widely concerning the penetration into and the distribution within the foetus.


Marine Drugs ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 55
Author(s):  
Synthia Michon ◽  
Florine Cavelier ◽  
Xavier J. Salom-Roig

Aurilides are a class of depsipeptides occurring mainly in marine cyanobacteria. Members of the aurilide family have shown to exhibit strong cytotoxicity against various cancer cell lines. These compounds bear a pentapeptide, a polyketide, and an α-hydroxy ester subunit in their structure. A large number of remarkable studies on aurilides have emerged since 1996. This comprehensive account summarizes the biological activities and total syntheses of natural compounds of the aurilide family as well as their synthetic analogues.


ChemInform ◽  
2016 ◽  
Vol 47 (24) ◽  
Author(s):  
Elisabeth K. Olsen ◽  
Espen Hansen ◽  
Lindon W. K. Moodie ◽  
Johan Isaksson ◽  
Kristina Sepcic ◽  
...  

2014 ◽  
Vol 18 (15) ◽  
pp. 2037-2042 ◽  
Author(s):  
Peter Keglevich ◽  
Andras Keglevich ◽  
Laszlo Hazai ◽  
Gyorgy Kalaus ◽  
Csaba Szantay

1978 ◽  
Vol 9 (4) ◽  
pp. 236-246 ◽  
Author(s):  
Mary K. Vaughan ◽  
John C. Little ◽  
Linda Y. Johnson ◽  
David E. Blask ◽  
George M. Vaughan ◽  
...  

ChemBioChem ◽  
2012 ◽  
Vol 13 (7) ◽  
pp. 982-986 ◽  
Author(s):  
Luigi Margarucci ◽  
Alessandra Tosco ◽  
Rosa De Simone ◽  
Raffaele Riccio ◽  
Maria Chiara Monti ◽  
...  

ChemInform ◽  
2015 ◽  
Vol 46 (10) ◽  
pp. no-no
Author(s):  
Peter Keglevich ◽  
Andras Keglevich ◽  
Laszlo Hazai ◽  
Gyorgy Kalaus ◽  
Csaba Szantay

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