Amperometric galectin-3 immunosensor-based gold nanoparticle-functionalized graphitic carbon nitride nanosheets and core–shell Ti-MOF@COFs composites

Nanoscale ◽  
2020 ◽  
Vol 12 (38) ◽  
pp. 19824-19832 ◽  
Author(s):  
Mehmet Lütfi Yola ◽  
Necip Atar

Antigen galectin-3 (GL-3), a member of β-galactoside proteins indicates cardiac fibrosis and is a significant biomarker for monitoring heart failure risk and death risk.

2010 ◽  
Vol 6 (2) ◽  
pp. 33 ◽  
Author(s):  
Christopher R deFilippi ◽  
G Michael Felker ◽  
◽  

For many with heart failure, including the elderly and those with a preserved ejection fraction, both risk stratification and treatment are challenging. For these large populations and others there is increasing recognition of the role of cardiac fibrosis in the pathophysiology of heart failure. Galectin-3 is a novel biomarker of fibrosis and cardiac remodelling that represents an intriguing link between inflammation and fibrosis. In this article we review the biology of galectin-3, recent clinical research and its application in the management of heart failure patients.


2019 ◽  
Vol 1091 ◽  
pp. 69-75 ◽  
Author(s):  
Na Wu ◽  
Yi-Ting Wang ◽  
Xiao-Yan Wang ◽  
Feng-Na Guo ◽  
Hui Wen ◽  
...  

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