Synthesis of aryl ethers of carbohydrates via reaction with arynes: selective O-arylation of trans-vicinal dihydroxyl groups in carbohydrates

New method for synthesis of 2-hetarylquinazolin-4(3H)-ones from 2-aminobenzamides and (2-azaaryl)methanes under transition-metal free conditions, featuring a wide substrate scope with a broad range of functional group tolerance under mild conditions.

Download Full-text

A cascade process for the synthesis of ortho-formyl allyl aryl ethers and 2H-chromen-2-ol derivatives from arynes via trapping of o-quinone methide with an activated alkene

Organic & Biomolecular Chemistry ◽

10.1039/c8ob02507j ◽

2019 ◽

Vol 17 (2) ◽

pp. 333-346 ◽

Cited By ~ 7

Author(s):

Abhilash Sharma ◽

Pranjal Gogoi

Keyword(s):

Transition Metal ◽

Direct Synthesis ◽

Quinone Methide ◽

Cascade Process ◽

Metal Free ◽

Synthetic Strategy ◽

Aryl Ethers ◽

Three Component Coupling

A transition-metal free synthetic strategy for the direct synthesis of ortho-formyl substituted allyl aryl ethers and 2H-chromen-2-ol derivatives via a cascade three-component coupling of arynes, activated alkene and N,N-dimethylformamide.

Download Full-text

Transition-metal free direct difluoromethylthiolation of electron-rich aromatics with difluoromethanesulfonyl chloride

Organic Chemistry Frontiers ◽

10.1039/c6qo00581k ◽

2017 ◽

Vol 4 (2) ◽

pp. 232-235 ◽

Cited By ~ 29

Author(s):

Xia Zhao ◽

Aoqi Wei ◽

Tianjiao Li ◽

Zhiyang Su ◽

Jun Chen ◽

...

Keyword(s):

Transition Metal ◽

New Method ◽

Metal Free

A new method for phosphine-mediated difluoromethylthiolation of indoles and other electron-rich aromatics using difluoromethanesulfonyl chloride was developed.

Download Full-text

ChemInform Abstract: Transition-Metal-Free Oxidative Amidation of Benzyl Alcohols with Amines Catalyzed by NaI: A New Method for the Synthesis of Benzamides.

ChemInform ◽

10.1002/chin.201510098 ◽

2015 ◽

Vol 46 (10) ◽

pp. no-no

Author(s):

Meghdad Karimi ◽

Dariush Saberi ◽

Kobra Azizi ◽

Marzban Arefi ◽

Akbar Heydari

Keyword(s):

Transition Metal ◽

New Method ◽

Benzyl Alcohols ◽

Metal Free ◽

Oxidative Amidation

Download Full-text

Single-step Syznthesis of Coenzyme Q0

Asian Journal of Applied Chemistry Research ◽

10.9734/ajacr/2018/v2i3-430080 ◽

2019 ◽

pp. 1-4

Author(s):

Yi-Yu Yan ◽

Yong-Fu Qiu ◽

Tian-Li Zhang ◽

Yu-Bei He ◽

Shi Qi ◽

...

Keyword(s):

Transition Metal ◽

Ammonium Persulfate ◽

Single Step ◽

New Method ◽

Metal Free ◽

One Step ◽

Coenzyme Q0

A new method for the preparation of 2-methyl-5,6-dimethoxy-1,4-benzoquinone (Coenzyme Q0) was developed. This improved process in one step by the oxidation of 3,4,5-trimethoxytoluene to coenzyme Q0 by simple oxidation using potassium or ammonium persulfate under transition -metal free conditions.

Download Full-text

Transition-metal-free persulfuration to construct unsymmetrical disulfides and mechanistic study of the sulfur redox process

Chemical Communications ◽

10.1039/c4cc09633a ◽

2015 ◽

Vol 51 (20) ◽

pp. 4208-4211 ◽

Cited By ~ 58

Author(s):

Xiao Xiao ◽

Minghao Feng ◽

Xuefeng Jiang

Keyword(s):

Natural Products ◽

Transition Metal ◽

Redox Process ◽

Biologically Active ◽

New Method ◽

Mechanistic Study ◽

Metal Free ◽

Active Moiety

A sulfur redox process has been developed between sulfinate and thiosulfate, which efficiently affords diverse unsymmetrical disulfides and provides a new method to modify pharmaceuticals and natural products with this biologically active moiety without extra oxidant or reductant.

Download Full-text

Transition-metal-free oxidative amidation of benzyl alcohols with amines catalyzed by NaI: a new method for the synthesis of benzamides

Tetrahedron Letters ◽

10.1016/j.tetlet.2014.07.085 ◽

2014 ◽

Vol 55 (39) ◽

pp. 5351-5353 ◽

Cited By ~ 18

Author(s):

Meghdad Karimi ◽

Dariush Saberi ◽

Kobra Azizi ◽

Marzban Arefi ◽

Akbar Heydari

Keyword(s):

Transition Metal ◽

New Method ◽

Benzyl Alcohols ◽

Metal Free ◽

Oxidative Amidation

Download Full-text

Transition-metal-free catalytic hydroboration reduction of amides to amines

Organic Chemistry Frontiers ◽

10.1039/d0qo01092h ◽

2020 ◽

Vol 7 (21) ◽

pp. 3515-3520

Author(s):

Wubing Yao ◽

Jiali Wang ◽

Aiguo Zhong ◽

Shiliang Wang ◽

Yinlin Shao

Keyword(s):

Transition Metal ◽

Selective Catalytic Reduction ◽

Catalytic Reduction ◽

Value Added ◽

Metal Free

The selective catalytic reduction of amides to value-added amine products is a desirable but challenging transformation.

Download Full-text

Deaminative carbonylative thioesterification of activated alkylamines with thiophenols under transition-metal-free conditions

Organic Chemistry Frontiers ◽

10.1039/d0qo01479f ◽

2021 ◽

Author(s):

Fengqian Zhao ◽

Xiao-Feng Wu

Keyword(s):

Free Radical ◽

Transition Metal ◽

Metal Free

A transition-metal-free radical carbonylation of activated alkylamines with thiophenols has been successfully developed. Various thioesters were selectively produced with moderate to good yields.

Download Full-text

Regioselective C3-H Trifluoromethylation of 2H-Indazole Under Transition-Metal-Free Photoredox Catalysis

10.26434/chemrxiv.7796603.v1 ◽

2019 ◽

Cited By ~ 1

Author(s):

Arumugavel Murugan ◽

Venkata Nagarjuna Babu ◽

Nagaraj Sabarinathan ◽

Sharada Duddu. S

Keyword(s):

Transition Metal ◽

Visible Light ◽

Practical Approach ◽

Hypervalent Iodine ◽

Radical Mechanism ◽

Photoredox Catalysis ◽

Metal Free

Here we report a visible-light-promoted metal-free regioselective C3-H trifluoromehtylation reaction that proceeds via radical mechanism and which supported by control experiments. The combination of photoredox catalysis and hypervalent iodine reagent provides a practical approach for the present trifluoromethylation reaction and synthesis of a library of trifluoromethylated indazoles.

Download Full-text