Palladium-catalyzed reductive cross-coupling between α-bromo carboxamides and terminal alkynes

2020 ◽  
Vol 7 (21) ◽  
pp. 3505-3508
Author(s):  
Muinat A. Aliyu ◽  
Bowen Li ◽  
He Yang ◽  
Wenjun Tang
Keyword(s):  
Cross Coupling ◽  
Sonogashira Coupling ◽  
Terminal Alkynes ◽  
Palladium Catalyzed

A Pd-catalyzed reductive cross-coupling between α-bromo carboxamides and terminal alkynes was developed featuring a radical pathway and distinct from the Sonogashira coupling.

Palladium-catalyzed carbonylative Sonogashira coupling of aryl diazonium salts with formic acid as the CO source: the effect of 1,3-butadiene

2017 ◽  
Vol 7 (21) ◽  
pp. 4924-4928 ◽  
Author(s):  
Fu-Peng Wu ◽  
Jin-Bao Peng ◽  
Xinxin Qi ◽  
Xiao-Feng Wu
Keyword(s):  
Formic Acid ◽  
Crucial Role ◽  
Cross Coupling ◽  
Diazonium Salts ◽  
Sonogashira Coupling ◽  
Terminal Alkynes ◽  
Palladium Catalyzed

An efficient carbonylative cross-coupling of aryl diazonium salts with terminal alkynes using formic acid as the CO source has been developed. And 1,3-butadiene was found to play a crucial role in this transformation.

Palladium Catalyzed Synthesis of Phenylquinoxaline-Alkyne Derivatives via Sonogashira Cross Coupling Reaction

2021 ◽  
Vol 43 (1) ◽  
pp. 95-95
Author(s):  
Rifhat Bibi Rifhat Bibi ◽  
Muhammad Yaseen Muhammad Yaseen ◽  
Haseen Ahmad Haseen Ahmad ◽  
Ismat Ullah Khan Ismat Ullah Khan ◽  
Shaista Parveen Shaista Parveen ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Sonogashira Reaction ◽  
Terminal Alkynes ◽  
Vinyl Halides ◽  
Sonogashira Coupling Reaction ◽  
Quinoxaline Derivatives ◽  
Palladium Catalyzed ◽  
High Yields ◽  
Alkyne Derivatives

Transition metals mediated cross coupling methodologies provide an extremely powerful versatile pathway in organic syntheses undoubtedly, a facile route for syntheses and derivatization of biologically important heterocycles from easily available precursors. Sonogashira coupling reaction, a leading method to Csp-Csp2 bond formation is one of the most important and rapid pathways to couple aryl/vinyl halides with terminal alkynes. Current research study deals with the synthesis of alkyne substituted quinoxaline derivatives. The quinoxalines class of aromatic heterocycles exhibits a wide variety of important biological potencies. Palladium catalyzed cross coupling process provided an effective synthetic practice for the synthesis of alkyne derivatives of quinoxaline. Vareity of terminal alkynes were coupled with 2-(4-bromophenyl)quinoxaline under optimized conditions for Sonogashira reaction, affording alkyne substituted quinoxaline derivatives in high yields. The optimized reaction conditions for coupling of range of terminal alkyne with quinoxaline basic core render this process significant for designing of medicinally interesting precursors.

ChemInform Abstract: Palladium-Catalyzed Aerobic Oxidative Cross-Coupling Reactions of Terminal Alkynes with Alkylzinc Reagents.

ChemInform ◽  
2010 ◽  
Vol 41 (31) ◽  
pp. no-no
Author(s):  
Mao Chen ◽  
Xiaolong Zheng ◽  
Wenqing Li ◽  
Jun He ◽  
Aiwen Lei
Keyword(s):  
Cross Coupling ◽  
Coupling Reactions ◽  
Terminal Alkynes ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed

Palladium-catalyzed denitrative Sonogashira-type cross-coupling of nitrobenzenes with terminal alkynes

2020 ◽  
Vol 56 (5) ◽  
pp. 790-793 ◽  
Author(s):  
Boya Feng ◽  
Yudong Yang ◽  
Jingsong You
Keyword(s):  
Bond Formation ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Terminal Alkynes ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed

Described herein is a palladium-catalyzed cross-coupling reaction between nitroarenes and terminal alkynes, offering a facile method for C(sp2)–C(sp) bond formation.

Palladium-Catalyzed Aerobic Oxidative Cross-Coupling Reactions of Terminal Alkynes with Alkylzinc Reagents

2010 ◽  
Vol 132 (12) ◽  
pp. 4101-4103 ◽  
Author(s):  
Mao Chen ◽  
Xiaolong Zheng ◽  
Wenqing Li ◽  
Jun He ◽  
Aiwen Lei
Keyword(s):  
Cross Coupling ◽  
Coupling Reactions ◽  
Terminal Alkynes ◽  
Cross Coupling Reactions ◽  
Palladium Catalyzed

Palladium-Catalyzed Desulfitative Cross-Coupling of Arylsulfonyl Hydrazides with Terminal Alkynes: A General Approach toward Functionalized Internal Alkynes

2017 ◽  
Vol 82 (13) ◽  
pp. 6764-6769 ◽  
Author(s):  
Liang-Wei Qian ◽  
Mengli Sun ◽  
Jianyu Dong ◽  
Qing Xu ◽  
Yongbo Zhou ◽  
...  
Keyword(s):  
Cross Coupling ◽  
Terminal Alkynes ◽  
Internal Alkynes ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Oxidative Cross-Coupling of N-Tosylhydrazones or Diazoesters with Terminal Alkynes: A Route to Conjugated Enynes.

ChemInform ◽  
2011 ◽  
Vol 42 (32) ◽  
pp. no-no
Author(s):  
Lei Zhou ◽  
Fei Ye ◽  
Jiachen Ma ◽  
Yan Zhang ◽  
Jianbo Wang
Keyword(s):  
Cross Coupling ◽  
Terminal Alkynes ◽  
Conjugated Enynes ◽  
Palladium Catalyzed
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