scholarly journals Two lathyrane diterpenoid stereoisomers containing an unusual trans-gem-dimethylcyclopropane from the seeds of Euphorbia lathyris

RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 3183-3189
Author(s):  
Linwei Li ◽  
Jianan Huang ◽  
Hui Lyu ◽  
Fuqin Guan ◽  
Pirui Li ◽  
...  
Keyword(s):  
Cell Line ◽  
U937 Cell ◽  
Inhibitory Effect ◽  
Euphorbia Lathyris

Two novel lathyrane-type diterpenoids, which possess a trans-gem-dimethylcyclopropane were obtained from seeds of Euphorbia lathyris. The Euphorbia factor L2b exhibited an inhibitory effect against U937 cell line with an IC50 value of 0.87 μM.

cDNA cloning of IL-1α and IL-1β from mRNA of U937 cell line

1987 ◽  
Vol 143 (1) ◽  
pp. 345-352 ◽  
Author(s):  
Tsutomu Nishida ◽  
Naoki Nishino ◽  
Masaaki Takano ◽  
Kazuyoshi Kawai ◽  
Keiko Bando ◽  
...  
Keyword(s):  
Cell Line ◽  
Cdna Cloning ◽  
U937 Cell

Degradation of the immunogenic peptide gp100280–288 by the monocyte-like U937 cell line

Peptides ◽  
2003 ◽  
Vol 24 (3) ◽  
pp. 371-378 ◽  
Author(s):  
Federica Albo ◽  
Antonella Cavazza ◽  
Bruno Giardina ◽  
Silvio Lippa ◽  
Mario Marini ◽  
...  
Keyword(s):  
Cell Line ◽  
U937 Cell ◽  
Immunogenic Peptide

scholarly journals Effect of Aspirin on Cell Growth of Human MG-63 Osteosarcoma Line

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
E. De Luna-Bertos ◽  
J. Ramos-Torrecillas ◽  
O. García-Martínez ◽  
L. Díaz-Rodríguez ◽  
C. Ruiz
Keyword(s):  
Cell Cycle ◽  
Cell Growth ◽  
Cell Line ◽  
Bone Tissue ◽  
Tissue Repair ◽  
Mg63 Cell ◽  
Pharmacological Action ◽  
Inhibitory Effect ◽  
Cell Cycle Analysis ◽  
Inflammatory Drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in bone tissue repair treatment for their pharmacological action. The objective of this study was to determine the effect of aspirin, on osteoblast growth, using MG63 cell line as osteoblast model. MTT spectrophotometry results showed that 20, 100, and 1000 μM aspirin doses have an inhibitory effect on growth. Cell cycle analysis revealed that aspirin doses of 100 and 1000 μM arrest the cell cycle in phase GO/G1. Parallel apoptosis/necrosis studies showed no changes in comparison to control cells after treatment with 1 or 10 μM aspirin but a significantly increased percentage of cells in apoptosis at doses of 20, 100, and 1000 μM. We highlight that treatment of osteoblast-like cells with 1000 μM aspirin increased not only the percentage of cells in apoptosis but also the percentage of necrotic cells, which was not observed in aspirin treatments at lower doses.

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