Ultra-small gold nanoparticles self-assembled by gadolinium ions for enhanced photothermal/photodynamic liver cancer therapy

Gold nanomaterials are widely used in biomedical research as drug delivery systems, imaging agents and therapeutic materials owing to their unique physicochemical properties and high biocompatibility. In this study, we...

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Thinking small, doing big: Current success and future trends in drug delivery systems for improving cancer therapy with special focus on liver cancer

Materials Science and Engineering C ◽

10.1016/j.msec.2018.11.001 ◽

2019 ◽

Vol 95 ◽

pp. 328-341 ◽

Cited By ~ 10

Author(s):

María J. Limeres ◽

Marcela A. Moretton ◽

Ezequiel Bernabeu ◽

Diego A. Chiappetta ◽

María L. Cuestas

Keyword(s):

Drug Delivery ◽

Cancer Therapy ◽

Liver Cancer ◽

Drug Delivery Systems ◽

Delivery Systems ◽

Special Focus ◽

Future Trends

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Development of Tri-component Copolymer Rods as Implantable Drug Delivery Systems for Liver Cancer Therapy

IFMBE Proceedings - World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany ◽

10.1007/978-3-642-03887-7_92 ◽

2009 ◽

pp. 317-320 ◽

Cited By ~ 1

Author(s):

N. Nasongkla ◽

P. Akarajiratun ◽

S. Hongeng

Keyword(s):

Drug Delivery ◽

Cancer Therapy ◽

Liver Cancer ◽

Drug Delivery Systems ◽

Delivery Systems ◽

Implantable Drug Delivery Systems

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Environment-responsive Polymeric Nanoparticles as Drug Delivery Systems for Cancer Therapy

ACTA AGRONOMICA SINICA ◽

10.3724/sp.j.1206.2013.00431 ◽

2013 ◽

Vol 40 (10) ◽

pp. 1039

Author(s):

Yang YANG ◽

Wen-Chuan SHE ◽

Kui LUO ◽

Zhong-Wei GU

Keyword(s):

Drug Delivery ◽

Cancer Therapy ◽

Drug Delivery Systems ◽

Polymeric Nanoparticles ◽

Delivery Systems

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Nanoparticle-based Drug Delivery Systems for Targeted Epigenetics Cancer Therapy

Current Drug Targets ◽

10.2174/1389450121666200514222900 ◽

2020 ◽

Vol 21 (11) ◽

pp. 1084-1098

Author(s):

Fengqian Chen ◽

Yunzhen Shi ◽

Jinming Zhang ◽

Qi Liu

Keyword(s):

Drug Delivery ◽

Side Effects ◽

Cancer Therapy ◽

Drug Delivery Systems ◽

Therapeutic Index ◽

Delivery Systems ◽

Epigenetic Therapy ◽

Cancer Therapies ◽

Therapeutic Benefits ◽

High Therapeutic Index

This review summarizes the epigenetic mechanisms of deoxyribonucleic acid (DNA) methylation, histone modifications in cancer and the epigenetic modifications in cancer therapy. Due to their undesired side effects, the use of epigenetic drugs as chemo-drugs in cancer therapies is limited. The drug delivery system opens a door for minimizing these side effects and achieving greater therapeutic benefits. The limitations of current epigenetic therapies in clinical cancer treatment and the advantages of using drug delivery systems for epigenetic agents are also discussed. Combining drug delivery systems with epigenetic therapy is a promising approach to reaching a high therapeutic index and minimizing the side effects.

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