Efficient Synthesis of Tetra- and Penta-substituted Benzenes via Domino Cycloaddition Reaction of pyridinium ylide and Chalcone o-Enolate

2021 ◽  
Author(s):  
Feng-Shun Xu ◽  
Chen Yan ◽  
Jing Sun ◽  
Chaoguo Yan

A very simple and high efficient synthetic protocol for tetra- and penta-substituted benzene derivatives has been provided by tetramethylguanidine (TMD) promoted reaction of 4-(N,N-dimethylamino)-1-phenacyl-pyridinium bromide with chalcone o-enolates in DMF...

ChemInform ◽  
2008 ◽  
Vol 39 (29) ◽  
Author(s):  
Qingqing Shao ◽  
Shujiang Tu ◽  
Chunmei Li ◽  
Longji Cao ◽  
Dianxiang Zhou ◽  
...  

2017 ◽  
Vol 33 (4) ◽  
pp. 520-524 ◽  
Author(s):  
Yanyan Ji ◽  
Bing Zhang ◽  
Wu Zhang ◽  
Bo Zhao ◽  
Hongbo Li ◽  
...  

The flash photolysis of phenols, anilines, nitrobenzenes and some other benzene derivatives results in a novel ring fission process and the production of cyclopentadienyl radicals. The spectra of cyclopentadienyl, and its derivatives obtained from doubly substituted benzenes, have been recorded and analysed in part. A spectrum attributed to phenyl nitrene has been observed after flash photolysis of ortho chloro aniline, ortho bromo aniline and phenyl isocyanate.


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