Hydroxyl Group-Directed, Tartaric Acid-Catalyzed Synthesis of meta-Functionalized Aryl Ethers and Phenols through Domino Conjugate Addition/Aromatization of para-Quinols

2021 ◽  
Author(s):  
Guoshu Chen ◽  
Jia-Hui Li ◽  
Shujie Chen ◽  
Wen-Xia Lin ◽  
Hai Ren ◽  
...  
Keyword(s):  
Tartaric Acid ◽  
Conjugate Addition ◽  
Single Step ◽  
Hydroxyl Group ◽  
Alkyl Ether ◽  
Three Component Reaction ◽  
Organoboronic Acids ◽  
Acid Catalyzed ◽  
Aryl Ethers

A tartaric acid-catalyzed three-component reaction of para-quinols, organoboronic acids, and alcohols is reported, leading to meta-alkenylated aryl alkyl ether in a single step. Moreover, meta-functionalized phenols could also be obtained...

ChemInform Abstract: (+)-Tartaric Acid-Catalyzed High Regio- and Stereoselective Aminobromination of Olefins.

ChemInform ◽  
2011 ◽  
Vol 42 (51) ◽  
pp. no-no
Author(s):  
Zhanguo Chen ◽  
Junfa Wei ◽  
Wenli Li ◽  
Yun Wang ◽  
Pengfei Zhao ◽  
...  
Keyword(s):  
Tartaric Acid ◽  
Acid Catalyzed

Three-component 3-(phosphoryl)methylindole synthesis from indoles, H-phosphine oxides and carbonyl compounds under metal-free conditions

2019 ◽  
Vol 21 (4) ◽  
pp. 792-797 ◽  
Author(s):  
Jiaoting Pan ◽  
Runmin Zhao ◽  
Jiami Guo ◽  
Dumei Ma ◽  
Ying Xia ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Indole Derivatives ◽  
Phosphine Oxides ◽  
One Pot ◽  
Metal Free ◽  
Three Component Reaction ◽  
Acid Catalyzed

The first facile and efficient acid-catalyzed three-component reaction of indoles, H-phosphine oxides and carbonyl compounds has been developed, providing a general, one-pot approach to structurally diverse C3-alkylated indole derivatives.

Rhodium-Catalyzed Asymmetric Conjugate Addition of Organoboronic Acids to Carbonyl-Activated Alkenyl Azaarenes

2020 ◽  
Vol 362 (15) ◽  
pp. 3142-3147 ◽  
Author(s):  
Huilong Zhu ◽  
Long Yin ◽  
Zhiqian Chang ◽  
Yuhan Wang ◽  
Xiaowei Dou
Keyword(s):  
Conjugate Addition ◽  
Organoboronic Acids

Chiral Spiro Phosphoric Acid-Catalyzed Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions

ACS Catalysis ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 6522-6529 ◽  
Author(s):  
Yi-Pan Li ◽  
Zi-Qi Li ◽  
Biying Zhou ◽  
Mao-Lin Li ◽  
Xiao-Song Xue ◽  
...  
Keyword(s):  
Phosphoric Acid ◽  
Conjugate Addition ◽  
Acid Catalyzed

scholarly journals A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles

2019 ◽  
Vol 15 ◽  
pp. 1061-1064 ◽  
Author(s):  
Alexei Lukin ◽  
Anna Bakholdina ◽  
Anna Kryukova ◽  
Alexander Sapegin ◽  
Mikhail Krasavin
Keyword(s):  
Lewis Acid ◽  
Primary Amine ◽  
Three Component Reaction ◽  
Acid Catalyzed ◽  
In Situ Generation

A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported base-promoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.

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