Rh-Catalyzed Diastereoselective Addition of Arylboronic Acids to α-Keto N-tert-Butanesulfinyl Aldimines: Synthesis of α-Amino Ketones

Author(s):  
Cece Wang ◽  
Lu Zhou ◽  
Jian Qiu ◽  
Kai Yang ◽  
Qiuling Song

Herein we present a diastereoselective addition of arylboronic acids to α-keto N-tert-butanesulfinyl aldimines catalyzed by Rh(I) catalyst. This reaction provides a practical method to deliver valuable chiral α-amino ketones with...

2020 ◽  
Vol 18 (43) ◽  
pp. 8886-8898
Author(s):  
Dwaipayan Das ◽  
Prasun Mukherjee ◽  
Asish R. Das

An efficient palladium catalyzed diastereoselective addition of arylboronic acids to complex spirocyclopropyl dinitriles is developed in the presence of a catalytic amount of DBSA as a Brønsted acid surfactant in aqueous media.


2019 ◽  
Vol 17 (32) ◽  
pp. 7558-7563 ◽  
Author(s):  
Yuanding Fang ◽  
Rong Zhao ◽  
Yuan Yao ◽  
Yang Liu ◽  
Denghu Chang ◽  
...  

An efficient and practical method for the ipso-hydroxylation of arylboronic acids was developed using TBHP and Cl3CCN under base-free conditions with blue-LED irradiation.


Synlett ◽  
2020 ◽  
Vol 31 (20) ◽  
pp. 2039-2042
Author(s):  
Minxin Li ◽  
Yanling Tang ◽  
Zewei Mao ◽  
Jinchun Gao ◽  
Gaoxiong Rao

AbstractA concise and practical method was developed for the protodeboronation of arylboronic acids under mild conditions in aqueous NaClO at 100 °C. The strategy is low-cost, transition-metal-free, and base-free.


RSC Advances ◽  
2016 ◽  
Vol 6 (49) ◽  
pp. 43605-43612 ◽  
Author(s):  
Chongren You ◽  
Fang Yao ◽  
Tao Yan ◽  
Mingzhong Cai

A highly efficient and practical method for the synthesis of N-arylsulfonamides has been developed by a heterogeneous copper-catalyzed Chan–Lam coupling between sulfonyl azides and boronic acids.


2019 ◽  
Vol 60 (39) ◽  
pp. 150859 ◽  
Author(s):  
Guangying Lu ◽  
Yaoyao Ren ◽  
Bin Dong ◽  
Bin Zhou ◽  
Jiangmeng Ren ◽  
...  

Author(s):  
E.M. Waddell ◽  
J.N. Chapman ◽  
R.P. Ferrier

Dekkers and de Lang (1977) have discussed a practical method of realising differential phase contrast in a STEM. The method involves taking the difference signal from two semi-circular detectors placed symmetrically about the optic axis and subtending the same angle (2α) at the specimen as that of the cone of illumination. Such a system, or an obvious generalisation of it, namely a quadrant detector, has the characteristic of responding to the gradient of the phase of the specimen transmittance. In this paper we shall compare the performance of this type of system with that of a first moment detector (Waddell et al.1977).For a first moment detector the response function R(k) is of the form R(k) = ck where c is a constant, k is a position vector in the detector plane and the vector nature of R(k)indicates that two signals are produced. This type of system would produce an image signal given bywhere the specimen transmittance is given by a (r) exp (iϕ (r), r is a position vector in object space, ro the position of the probe, ⊛ represents a convolution integral and it has been assumed that we have a coherent probe, with a complex disturbance of the form b(r-ro) exp (iζ (r-ro)). Thus the image signal for a pure phase object imaged in a STEM using a first moment detector is b2 ⊛ ▽ø. Note that this puts no restrictions on the magnitude of the variation of the phase function, but does assume an infinite detector.


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