scholarly journals Impact of type-1 collagen hydrogel density on integrin-linked morphogenic response of SH-SY5Y neuronal cells

RSC Advances ◽  
2021 ◽  
Vol 11 (52) ◽  
pp. 33124-33135
Author(s):  
D. Merryweather ◽  
S. R. Moxon ◽  
A. J. Capel ◽  
N. M. Hooper ◽  
M. P. Lewis ◽  
...  
Keyword(s):  
Neuronal Cells ◽  
Cellular Metabolism ◽  
Collagen Hydrogel ◽  
Morphogenic Response ◽  
Cytoskeletal Tension

Cellular metabolism and behaviour is closely linked to cytoskeletal tension and scaffold mechanics.

scholarly journals Herpes simplex virus-mediated human hypoxanthine-guanine phosphoribosyltransferase gene transfer into neuronal cells.

1988 ◽  
Vol 8 (1) ◽  
pp. 457-460 ◽  
Author(s):  
T D Palella ◽  
L J Silverman ◽  
C T Schroll ◽  
F L Homa ◽  
M Levine ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
Neurological Dysfunction ◽  
Hprt Gene ◽  
Hypoxanthine Guanine Phosphoribosyltransferase ◽  
Simplex Virus

The virtually complete deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a devastating neurological disease, Lesch-Nyhan syndrome. Transfer of the HPRT gene into fibroblasts and lymphoblasts in vitro and into hematopoietic cells in vivo has been accomplished by other groups with retroviral-derived vectors. It appears to be necessary, however, to transfer the HPRT gene into neuronal cells to correct the neurological dysfunction of this disorder. The neurotropic virus herpes simplex virus type 1 has features that make it suitable for use as a vector to transfer the HPRT gene into neuronal tissue. This report describes the isolation of an HPRT-deficient rat neuroma cell line, designated B103-4C, and the construction of a recombinant herpes simplex virus type 1 that contained human HPRT cDNA. These recombinant viruses were used to infect B103-4C cells. Infected cells expressed HPRT activity which was human in origin.

scholarly journals Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection

Virology ◽  
1985 ◽  
Vol 142 (2) ◽  
pp. 398-405
Author(s):  
Alan L. Goldin ◽  
Rozanne M. Sandri-Goldin ◽  
Joseph C. Glorioso ◽  
Myron Levine
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
Cellular Protein ◽  
Simplex Virus

Herpes simplex virus type 1 modulates cellular gene expression during quiescent infection of neuronal cells

2008 ◽  
Vol 153 (7) ◽  
pp. 1335-1345 ◽  
Author(s):  
Robert J. Danaher ◽  
Brandon S. McGarrell ◽  
Arnold J. Stromberg ◽  
Craig S. Miller
Keyword(s):  
Gene Expression ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
Cellular Gene ◽  
Cellular Gene Expression ◽  
Simplex Virus

P2-235: APP processing induced by herpes simplex virus type 1 (HSV-1) results in the production of several APP fragments and Aβ accumulation in human and rat neuronal cells

2010 ◽  
Vol 6 ◽  
pp. S382-S383
Author(s):  
Anna T. Palamara ◽  
Giovanna De Chiara ◽  
Maria E. Marcocci ◽  
Livia Civitelli ◽  
Roberto Piacentini ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
App Processing ◽  
Simplex Virus ◽  
Hsv 1

Human immunodeficiency virus type-1 vulnerates nascent neuronal cells

2008 ◽  
Vol 52 (2) ◽  
pp. 78-88 ◽  
Author(s):  
Hiroko Kitayama ◽  
Yoshiharu Miura ◽  
Yoshinori Ando ◽  
Yoshio Koyanagi
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Neuronal Cells ◽  
Immunodeficiency Virus
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