Cationic polymeric template-mediated preparation of silica nanocomposites

Soft Matter ◽  
2021 ◽  
Author(s):  
Xiaoning Sun ◽  
Xueying Yu ◽  
Fang Cheng ◽  
Wei He

Cationic templates mediating biomimetic silica synthesis include biomacromolecules, water-soluble synthetic polymers, latex particles, micelles, microgels, etc., leading to nanocomposites with great potentials for a variety of applications.

Author(s):  
Ratnaparkhi M.P. ◽  
Karnawat G.R. ◽  
Andhale R.S.

Oral route is most preferable route of administration for various drugs, because it is convenient, economical, safest route. Fast dissolving tablets are popular nowadays, as they disintegrated in mouth within a few seconds without using water for swallow. Problems like Dysphagia in pediatric and geriatric patients have been overcome by formulating Fast dissolving tablet. Natural polymers are preferable because they are chemically inert, nontoxic, less expensive, biodegradable, and available easily than synthetic polymers. Natural polymers are obtained from the natural origin so they are devoid of any side effect. It is proved from the previous studies that Natural polymers are more-safe and effective than the synthetic polymers. Natural polymers improve the properties of tablet and they are used as binder, diluent, superdisintegrant, they also enhance the solubility of poorly water-soluble drug, decrease the disintegration time and provide nutritional supplement. The aim of the present article is to study various natural polymers used in fast dissolving tablets.


1985 ◽  
Vol 108 (1) ◽  
pp. 83-94 ◽  
Author(s):  
Christian Bindschaedler ◽  
Robert Gurny ◽  
Eric Doelker ◽  
Nikolaos A Peppas

2009 ◽  
Vol 24 (5) ◽  
pp. 1700-1708 ◽  
Author(s):  
Mei-Keat Liang ◽  
Siddharth V. Patwardhan ◽  
Elena N. Danilovtseva ◽  
Vadim V. Annenkov ◽  
Carole C. Perry

Histidine is an amino acid present in proteins involved in biosilica formation and often found in peptides identified during phage display studies but its role(s) and the extent of its involvement in the silica precipitation process is not fully understood. In this contribution we describe results from an in vitro silicification study conducted using poly-histidine (P-His) and a series of different molecular weight synthetic polymers containing the imidazole functionality (polyvinylimidazole, PVI) for comparison. We show that the presence of imidazole from PVI or P-His is able to catalyze silicic acid condensation; the effect being greater for P-His. The catalytic mechanism is proposed to involve the dual features of the imidazole group—its ability to form hydrogen bonds with silicic acid and electrostatic attraction toward oligomeric silicic acid species.


Processes ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 137
Author(s):  
Awais Ahmad ◽  
N.M. Mubarak ◽  
Fakiha Tul Jannat ◽  
Tayyaba Ashfaq ◽  
Carlo Santulli ◽  
...  

Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.


2020 ◽  
Vol 181 ◽  
pp. 115931 ◽  
Author(s):  
Sven Huppertsberg ◽  
Daniel Zahn ◽  
Frances Pauelsen ◽  
Thorsten Reemtsma ◽  
Thomas P. Knepper

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