A highly sensitive electrochemical cytosensor based on triple signal amplification strategy by using both nanozyme and DNAzyme.

Author(s):  
Jinxia Liu ◽  
Xiaodi Liu ◽  
Luxia Yang ◽  
Aiting Cai ◽  
Xiaobo Zhou ◽  
...  

The development of sensitive cytosensor was beneficial to the early diagnosis and treatment of cancer. Herein, highly sensitive cytosensing was achieved by applying triple signal amplification strategies with Fe3O4@Au nanozymes...

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.


2015 ◽  
Vol 738-739 ◽  
pp. 56-60
Author(s):  
Shu Xian Chen ◽  
Jing Liu ◽  
Dao Dong Pan ◽  
Ning Gan

An enzyme amplified immunosensor for highly sensitive detection of Ractopamine (RAC) in foodstuff was developed based on quartz crystal microbalance (QCM). The high sensitivity was achieved by enzyme-AuNPs signal amplification strategy and magnetic β-cyclodextrins (β-CD) enrichment capacity. The novel QCM immunosensor which combines with the advantages of high selectivity of immunoassays and the high sensitivity of QCM has been developed for the determination of trace residues of RAC in food production. Under optimum conditions, the differences in the frequencies (∆f) of the QCM were proportional to the concentration of RAC over the range from 0.01 to 10 ng mL-1. The minimal detection limit was 0.01 ng mL-1. Due to its high sensitivity, acceptable stability and good selectivity, the immunosensor realized reliable quantification of RAC in real foodstuff. The proposed project has the potential to become a successful on-site screening method in food safety.


2014 ◽  
Vol 50 (73) ◽  
pp. 10718-10721 ◽  
Author(s):  
Peng He ◽  
Wenping Qiao ◽  
Lijun Liu ◽  
Shusheng Zhang

A SPR bioassay was developed for the detection of DNA and Ramos cells by combining the target-triggered isothermal exponential amplification with MNP-based RCA.


RSC Advances ◽  
2013 ◽  
Vol 3 (45) ◽  
pp. 22868 ◽  
Author(s):  
Zhanjun Yang ◽  
Shufen Luo ◽  
Hua Dai ◽  
Juan Li ◽  
Xin'an Jiao ◽  
...  

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