The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement
Keyword(s):
We describe the first human RNase 6 crystal structure in complex with sulfate anions. Kinetic analysis, site-directed mutagenesis and molecular dynamics simulations identified novel substrate recognition and cleavage sites.
2009 ◽
Vol 74
(4)
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pp. 808-819
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2017 ◽
Vol 74
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pp. 344-351
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2015 ◽
Vol 71
(2)
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pp. 283-292