scholarly journals Biological insights into the expression of translation initiation factors from recombinant CHOK1SV cell lines and their relationship to enhanced productivity

2015 ◽  
Vol 472 (3) ◽  
pp. 261-273 ◽  
Author(s):  
Emma J. Mead ◽  
Rosalyn J. Masterton ◽  
Marc Feary ◽  
Olga Obrezanova ◽  
Lin Zhang ◽  
...  
Keyword(s):  
Translation Initiation ◽  
Chinese Hamster Ovary ◽  
Closed Loop ◽  
Chinese Hamster Ovary Cells ◽  
Recombinant Antibody ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Initiation Factors ◽  
Translation Initiation Factors ◽  
Antibody Productivity

We show for translation initiation factors involved in formation of the closed loop mRNA, their expression is associated with recombinant antibody productivity in Chinese hamster ovary cells and maintaining these is important in determining the cells capacity for antibody productivity.

LINE‐1 vectors mediate recombinant antibody gene transfer by retrotransposition in Chinese hamster ovary cells

2021 ◽  
pp. 2000620
Author(s):  
Feiyang Zheng ◽  
Yoshinori Kawabe ◽  
Mai Murakami ◽  
Mamika Takahashi ◽  
Kyoka Nishihata ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Recombinant Antibody ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Antibody Gene

scholarly journals Stable microRNA expression enhances therapeutic antibody productivity of Chinese hamster ovary cells

2013 ◽  
Vol 20 ◽  
pp. 157-166 ◽  
Author(s):  
Michaela Strotbek ◽  
Lore Florin ◽  
Jennifer Koenitzer ◽  
Anne Tolstrup ◽  
Hitto Kaufmann ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Microrna Expression ◽  
Therapeutic Antibody ◽  
Ovary Cells ◽  
Antibody Productivity

Engineering mRNA Translation Initiation to Enhance Transient Gene Expression in Chinese Hamster Ovary Cells

2003 ◽  
Vol 19 (1) ◽  
pp. 121-129 ◽  
Author(s):  
M.F. Underhill ◽  
C. Coley ◽  
J.R. Birch ◽  
A. Findlay ◽  
R. Kallmeier ◽  
...  
Keyword(s):  
Gene Expression ◽  
Translation Initiation ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Transient Gene Expression ◽  
Chinese Hamster ◽  
Mrna Translation ◽  
Ovary Cells
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