Iron Absorption in Chronic Renal Disease

1970 ◽  
Vol 38 (2) ◽  
pp. 191-196 ◽  
Author(s):  
J. W. Eschbach ◽  
J. D. Cook ◽  
C. A. Finch
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Iron Overload ◽  
Iron Absorption ◽  
Chronic Renal Disease ◽  
Iron Depletion ◽  
Isotope Technique ◽  
Double Isotope

1. Absorption of inorganic iron was studied in thirty-four patients with chronic renal failure by a double isotope technique. 2. Eight patients with normal iron balance had a mean absorption of 3·5%, ten patients with iron overload had a mean absorption of 3·6%, and sixteen patients with iron depletion had a mean absorption of 58%. Thus, alterations in absorption appeared to be related to disturbances in iron balance. 3. The rate of erythropoiesis had no evident effect on iron absorption nor did the degree of anaemia. 4. The presence of renal disease and the degree of azotaemia likewise did not appear to affect absorption.

scholarly journals Chronic Renal Failure, Cachexia, and Ghrelin

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
A. Laviano ◽  
Z. Krznaric ◽  
K. Sanchez-Lara ◽  
I. Preziosa ◽  
A. Cascino ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Food Intake ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Contributing Factors ◽  
Protein Energy Wasting ◽  
Protein Energy ◽  
Stage Renal Disease ◽  
End Stage

Protein energy wasting is frequently observed in patients with advanced chronic renal failure and end-stage renal disease. Anorexia and reduced food intake are critical contributing factors and negatively impact on patients' survival. Ghrelin is a prophagic peptide produced by the stomach and acting at the hypothalamic level to increase the activity of orexigenic neurons. In patients with chronic renal disease, plasma levels are increased as a likely effect of reduced renal clearance. Nevertheless, patients' food intake is significantly reduced, suggesting inflammation-mediated resistance of hypothalamic nuclei to peripheral signals. A number of forms of evidence show that ghrelin resistance could be overcome by the administration of exogenous ghrelin. Therefore, ghrelin has been proposed as a potential strategy to improve food intake in chronic renal failure patients with protein energy wasting. Preliminary data are encouraging although larger prospective clinical trials are needed to confirm the results and to identify those patients who are likely to benefit most from the administration of exogenous ghrelin.

Dietary Assessment of Patients Suffering From Chronic Renal Failure With Complications

2020 ◽  
pp. 46-50
Author(s):  
OJS Admin
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Glomerular Filtration ◽  
Chronic Renal Disease ◽  
Dietary Assessment ◽  
Clinical Manifestations ◽  
Major Health ◽  
Day By Day ◽  
Major Health Issue

Chronic renal disease is generally referred as impaired functioning of kidneys. Occurrence of kidney damage, increased loss of albumin in urine and a decreased glomerular filtration (GFR) rate are the clinical manifestations of chronic renal disease. It is a major health issue worldwide and the rate of this disease is increasing day by day.

scholarly journals Systemic conditions, oral findings and dental management of chronic renal failure patients: general considerations and case report

2006 ◽  
Vol 17 (2) ◽  
pp. 166-170 ◽  
Author(s):  
Mahmud Juma Abdalla Abdel Hamid ◽  
Claus Dieter Dummer ◽  
Lourenço Schmidt Pinto
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Chronic Renal Failure ◽  
Periodontal Disease ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Systemic Disease ◽  
Frequent Occurrence ◽  
Oral Manifestations ◽  
Dental Management

Chronic renal failure is a relatively common systemic disease. Systemic abnormalities such as anemia, platelet disorders and hypertension as well as oral manifestations including xerostomia, uremic stomatitis, periodontal disease and maxillary and mandibular radiographic alterations can be observed in individuals with chronic renal disease. In view of its frequent occurrence and the need of knowledge by dentists dealing with this condition, this paper discusses the most important issues regarding chronic renal failure, addressing its systemic and oral manifestations and the dental management of chronic renal patients. A case report is presented.

Coagulation Factor XIII and Serum Triglycerides in Patients with Chronic Renal Disease on Conservative and Regular Dialysis Treatment

1979 ◽  
Author(s):  
F. Carmassi ◽  
G. Mariani ◽  
R. Palla ◽  
L. Fusani ◽  
R. Dianchi
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Factor Xiii ◽  
Chronic Renal Disease ◽  
Coagulation Factor ◽  
Chronic Hemodialysis ◽  
Serum Triglycerides ◽  
Coagulation Factor Xiii ◽  
Regular Dialysis Treatment

The behaviour of coagulation factor XIII (fibrin stabilizing factor, FSF) and of serum triglycerides was studied in patients with chronic renal disease, using a specific antiserum to the active subunit (FSFA) for the direct measurement of the active fraction according to the Laurell’s method. The plasma FSFA concentration was measured in the following patients: I) 31 patients with chronic renal disease and serum creatinine below 1.5 mg/dl; II) 41 patients with chronic renal failure on conservative treatment; III) 53 chronic uremic patients on regular hemodialysis. FSFA concentration was significantly higher than normal (P<0.005) in the patients with chronic renal disease without renal failure, and similarly increased in the 41 patients with chronic renal failure on conservative therapy (P<0.001), as well as in the patients on chronic hemodialysis (P<0.001). Plasma FSFA levels were significantly higher in those patients with serum triglycerides above the upper normal limit and a significant positive correlation was found between serum triglycerides and FSFA plasma levels. These findings suggest a possible interaction of FSF with blood VLDLs in the genesis of atherosclerosis, early and severe complication of uremia.

THE PLASMA 17-HYDROXYCORTICOSTEROID LEVELS IN ACUTE AND CHRONIC RENAL FAILURE

1961 ◽  
Vol 39 (10) ◽  
pp. 1617-1624 ◽  
Author(s):  
A. J. Blair ◽  
R. O. Morgen ◽  
J. C. Beck
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Chronic Renal Disease

The free and glucuronide fractions of the plasma 17-hydroxycorticosteroids have been determined on specimens from 14 adult controls, 7 patients with chronic renal disease, and 11 patients with acute renal failure. The results have been statistically analyzed. Both free and glucuronide fractions were shown to be elevated in cases of acute renal failure while neither was significantly altered in the cases of chronic renal disease. The changes in these fractions during diuresis and hemodialysis in a few cases of acute renal failure are also reported. The possible mechanisms for these findings are briefly discussed.

scholarly journals Food intake pattern and nutritional status of hemodialytic patients

2021 ◽  
Vol 6 (4) ◽  
pp. 746-753
Author(s):  
Mousumi Akter ◽  
Farzana Alam
Keyword(s):  
Renal Failure ◽  
Nutritional Status ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Personal Information ◽  
Hemodialysis Patients ◽  
Dietary Recall ◽  
Arm Circumference ◽  
Common Etiology ◽  
Case Files

The incidence of renal disease is increasing at an alarming rate in Bangladesh. Malnutrition is directly correlated with the prevalence with these diseases. A total of 120 dialysis patients from both sexes having mean age 45±13. 79 years undergoing hemodialysis were enrolled for the study in Khulna city, Bangladesh. Information regarding disease history and associated co morbidities were collected from patient’s files. The personal information, prevalent vices, exercise behavior, dietary modifications and clinical and health status of the patients were recorded by using pre-tested questionnaire. Etiology of the chronic renal disease, complications and biochemical parameters were documented from the case files. Renal failure was more prevalent among male than in female. Diabetes mellitus (31.67%) were the most common etiology for chronic renal failure. Pallor of eyes was the most prevailing sign and the most common symptoms are breathlessness (98%), oliguria (88%), anorexia (67%) and nausea (60%). Nutritional status was assessed by anthropometric measurements using body mass index (BMI), mid arm circumference (MAC) and waist hip ratio (WHR). According to BMI, 43% male are grouped in normal category whereas majority of females (52%) are underweight with no overweight female respondents. 80% male had low adequacy of energy whereas all the female patients had adequacy of energy, carbohydrate and protein on low level. Dietary data was obtained by using 24-hour dietary recall and food frequency questionnaire. Actual intake of calories, protein, fats and minerals was lower than the recommended intake for hemodialysis patients. More than 50 percent of patient on hemodialysis were at risk of malnutrition. Around 32% respondents included fruits as per doctor’s advice whereas water and salted foods were restricted to three fourth of patients to protect kidney. Proper assessment of nutritional status, nutritional management and dietary modification can play a central role in preventing malnutrition of hemodialysis patients. Asian J. Med. Biol. Res. December 2020, 6(4): 746-753

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