scholarly journals Systemic conditions, oral findings and dental management of chronic renal failure patients: general considerations and case report

2006 ◽  
Vol 17 (2) ◽  
pp. 166-170 ◽  
Author(s):  
Mahmud Juma Abdalla Abdel Hamid ◽  
Claus Dieter Dummer ◽  
Lourenço Schmidt Pinto
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Chronic Renal Failure ◽  
Periodontal Disease ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Systemic Disease ◽  
Frequent Occurrence ◽  
Oral Manifestations ◽  
Dental Management

Chronic renal failure is a relatively common systemic disease. Systemic abnormalities such as anemia, platelet disorders and hypertension as well as oral manifestations including xerostomia, uremic stomatitis, periodontal disease and maxillary and mandibular radiographic alterations can be observed in individuals with chronic renal disease. In view of its frequent occurrence and the need of knowledge by dentists dealing with this condition, this paper discusses the most important issues regarding chronic renal failure, addressing its systemic and oral manifestations and the dental management of chronic renal patients. A case report is presented.

scholarly journals Chronic Renal Failure, Cachexia, and Ghrelin

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
A. Laviano ◽  
Z. Krznaric ◽  
K. Sanchez-Lara ◽  
I. Preziosa ◽  
A. Cascino ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Food Intake ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
Contributing Factors ◽  
Protein Energy Wasting ◽  
Protein Energy ◽  
Stage Renal Disease ◽  
End Stage

Protein energy wasting is frequently observed in patients with advanced chronic renal failure and end-stage renal disease. Anorexia and reduced food intake are critical contributing factors and negatively impact on patients' survival. Ghrelin is a prophagic peptide produced by the stomach and acting at the hypothalamic level to increase the activity of orexigenic neurons. In patients with chronic renal disease, plasma levels are increased as a likely effect of reduced renal clearance. Nevertheless, patients' food intake is significantly reduced, suggesting inflammation-mediated resistance of hypothalamic nuclei to peripheral signals. A number of forms of evidence show that ghrelin resistance could be overcome by the administration of exogenous ghrelin. Therefore, ghrelin has been proposed as a potential strategy to improve food intake in chronic renal failure patients with protein energy wasting. Preliminary data are encouraging although larger prospective clinical trials are needed to confirm the results and to identify those patients who are likely to benefit most from the administration of exogenous ghrelin.

Dietary Assessment of Patients Suffering From Chronic Renal Failure With Complications

2020 ◽  
pp. 46-50
Author(s):  
OJS Admin
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Glomerular Filtration ◽  
Chronic Renal Disease ◽  
Dietary Assessment ◽  
Clinical Manifestations ◽  
Major Health ◽  
Day By Day ◽  
Major Health Issue

Chronic renal disease is generally referred as impaired functioning of kidneys. Occurrence of kidney damage, increased loss of albumin in urine and a decreased glomerular filtration (GFR) rate are the clinical manifestations of chronic renal disease. It is a major health issue worldwide and the rate of this disease is increasing day by day.

Iron Absorption in Chronic Renal Disease

1970 ◽  
Vol 38 (2) ◽  
pp. 191-196 ◽  
Author(s):  
J. W. Eschbach ◽  
J. D. Cook ◽  
C. A. Finch
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Iron Overload ◽  
Iron Absorption ◽  
Chronic Renal Disease ◽  
Iron Depletion ◽  
Isotope Technique ◽  
Double Isotope

1. Absorption of inorganic iron was studied in thirty-four patients with chronic renal failure by a double isotope technique. 2. Eight patients with normal iron balance had a mean absorption of 3·5%, ten patients with iron overload had a mean absorption of 3·6%, and sixteen patients with iron depletion had a mean absorption of 58%. Thus, alterations in absorption appeared to be related to disturbances in iron balance. 3. The rate of erythropoiesis had no evident effect on iron absorption nor did the degree of anaemia. 4. The presence of renal disease and the degree of azotaemia likewise did not appear to affect absorption.

scholarly journals Chronic kidney disease and periodontal disease. Case report

2018 ◽  
Vol 21 (1) ◽  
pp. 133
Author(s):  
Camilla Magnoni Moretto Nunes ◽  
Camila Lopes Ferreira ◽  
Daniella Vicensotto Bernardo ◽  
Andréa Carvalho De Marco ◽  
Mauro Pedrine Santamaria ◽  
...  
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Chronic Renal Failure ◽  
Periodontal Disease ◽  
Periodontal Diseases ◽  
Treatment Plan ◽  
Clinical Manifestations ◽  
Disease Process ◽  
Periodontal Treatment ◽  
Disease Case

<p>Chronic renal disease promotes a decrease on kidneys filterability and nitrogen products accumulation on blood, electrolyte and system endocrine functions imbalance. Among the many clinical manifestations of chronic renal failure (CRF) in the oral cavity, there are: dry mouth, uremic stomatitis, radiographic changes in maxillary and jaw bones and accumulation of calculus on the teeth that increases levels of periodonto pathogenic microorganisms able to lead a periodontal tissue destruction and also have the potential to act from a distance on other organs, e.g. the kidneys. Thus, it becomes evident that a periodontal treatment of patients suffering from chronic renal failure is crucial for maintaining their general health conditions and a subsequent successful organ transplant.Thus, the objectives of this case report were to highlight how important the periodontal treatment is for chronic renal failure patients and to demonstrate improvements in their clinical condition through the treatment plan proposed herein. A patient with 43 years old carrier generalized moderate chronic periodontitis and CRF was submitted to scaling and root planning sessions, and later surgical access for scaling where the basic treatment not resulted in a resolution of the inflammatory periodontal process. The results obtained from a well-developed periodontal treatment and an effective cooperation of patient showed satisfactory results with periodontal disease process resolution or stabilization.Thus, periodontal treatment and patient compliance were crucial for the improvement of periodontal clinical conditions enabling a future successful renal transplantation.</p><p><strong>Keywords</strong></p><p>Dental care; Periodontal diseases; Renal insufficiency.</p>

Coagulation Factor XIII and Serum Triglycerides in Patients with Chronic Renal Disease on Conservative and Regular Dialysis Treatment

1979 ◽  
Author(s):  
F. Carmassi ◽  
G. Mariani ◽  
R. Palla ◽  
L. Fusani ◽  
R. Dianchi
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Disease ◽  
Factor Xiii ◽  
Chronic Renal Disease ◽  
Coagulation Factor ◽  
Chronic Hemodialysis ◽  
Serum Triglycerides ◽  
Coagulation Factor Xiii ◽  
Regular Dialysis Treatment

The behaviour of coagulation factor XIII (fibrin stabilizing factor, FSF) and of serum triglycerides was studied in patients with chronic renal disease, using a specific antiserum to the active subunit (FSFA) for the direct measurement of the active fraction according to the Laurell’s method. The plasma FSFA concentration was measured in the following patients: I) 31 patients with chronic renal disease and serum creatinine below 1.5 mg/dl; II) 41 patients with chronic renal failure on conservative treatment; III) 53 chronic uremic patients on regular hemodialysis. FSFA concentration was significantly higher than normal (P<0.005) in the patients with chronic renal disease without renal failure, and similarly increased in the 41 patients with chronic renal failure on conservative therapy (P<0.001), as well as in the patients on chronic hemodialysis (P<0.001). Plasma FSFA levels were significantly higher in those patients with serum triglycerides above the upper normal limit and a significant positive correlation was found between serum triglycerides and FSFA plasma levels. These findings suggest a possible interaction of FSF with blood VLDLs in the genesis of atherosclerosis, early and severe complication of uremia.

scholarly journals Oral Manifestations and Dental Management of Patients with Chronic Renal Failure on Hemodialysis

2018 ◽  
Vol 26 (4) ◽  
pp. 158-163
Author(s):  
Nazish Ashfaq Khan ◽  
Shairose Aziz ◽  
Maria Kwiatowski ◽  
Farrukh Anwar Mirza ◽  
Reza Haider ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Oral Manifestations ◽  
Dental Management

The Biochemical Effects of Non-surgical Periodontal Therapy in Patients with and without Chronic Renal Disease

2017 ◽  
Vol 68 (3) ◽  
pp. 605-607
Author(s):  
Cerasela Dorina Sincar ◽  
Nicoleta Ioanid ◽  
Ioana Rudnic ◽  
Ioana Martu ◽  
Sorina Mihaela Solomon ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Periodontal Disease ◽  
Renal Disease ◽  
Chronic Periodontitis ◽  
Chronic Renal Disease ◽  
Systemic Disease ◽  
Systemic Inflammatory Response ◽  
Periodontal Therapy ◽  
Periodontal Treatment ◽  
Control Group

Recent studies have shown an association between high levels of biomarkers and periodontitis, association which decreases after the periodontal treatment. Because of this association with systemic inflammatory response, chronic periodontitis was recently included as a risk factor for chronic renale disease. Specifically, in this study we hypothesized that a part of chronic inflammatory response observed in patients with chronic renale disease is due to physiopathological reactions caused by the presence of chronic periodontitis, which, during the course of its evolution, induces an increase in the expression of inflammatory markers. Patients were divided into two groups: the first group consisted of patients with chronic renale disease and periodontal disease who were undergoing periodontal treatment (test group) and the second group, control group, composed of patients without any systemic disease, but who experienced moderate to severe chronic periodontitis, also periodontal treated. Blood samples were taken for biochemical analysis at baseline and at 3 months after periodontal therapy. Venous blood was collected in vacuum tubes between 7:00 am and 9:00 am after 12 hours after the last meal. A tube containing EDTA was analyzed for blood following parameters: albumin, uric acid, creatinin, urea. An association between periodontal disease and renale disease is often found in studies using a population where the renale disease is already diagnosed. In these cases, duration of renal end stage and type of topical and systemic treatment administered to patients significantly affect the association. Therefore, we have shown that periodontitis may promote any detectable changes in renal function. Thus, by analogy, in this study the test groups and control groups were compared not only with each other but also comparative analyzes were performed based on the reference values of markers of renal dysfunction. We think it could be plausible existence of a causal link between periodontal disease and chronic renal disease both by glomerular invasion by periodontal pathogens, directly and indirectly through systemic inflammatory effect caused by chronic periodontitis. Success of periodontal therapy reduce systemic inflammatory response and decreases levels of biochemicals markers indicating that this may be an important intervention therapy in patients with chronic renale disease.

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