Effects of Bolus Holding on Respiratory–Swallow Coordination in Parkinson's Disease

2021 ◽  
pp. 1-17
Author(s):  
James A. Curtis ◽  
Avery E. Dakin ◽  
Michelle S. Troche
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pause Duration ◽  
Lung Volumes ◽  
Flexible Laryngoscopy ◽  
Respiratory Inductive Plethysmography ◽  
Respiratory Phase ◽  
Lower Lung ◽  
Respiratory Movements ◽  
Inductive Plethysmography

Purpose: The aim of this study was to examine the effects of bolus holding on respiratory–swallow coordination (RSC) in people with Parkinson's disease (PD). Method: People with PD were prospectively recruited to undergo RSC assessment using simultaneous respiratory inductive plethysmography and flexible laryngoscopy. During RSC assessment, participants swallowed 5-ml thin liquid boluses during held and nonheld swallowing tasks. Measures of RSC were analyzed for each swallow, which included respiratory pause duration, lung volume at swallow initiation, respiratory phase patterning, and the presence of paradoxical respiratory movements. Multilevel statistical modeling was used to determine if differences in RSC were present between the held and nonheld tasks. Results: Thirty-three participants were enrolled. When compared to the nonheld swallows, the held swallows exhibited shorter respiratory pauses ( p = .001, R 2 = .019), lower lung volumes at swallow initiation ( p < .001, R 2 = .116), more frequent exhale–swallow–exhale patterns ( p < .001, OR = 4.30), and less frequent paradoxical respiratory movements ( p = .001, OR = 0.43). Conclusions: Findings from this study revealed that bolus holding significantly influences RSC in people with PD. This demonstrates that bolus holding may be an efficacious strategy to immediately improve RSC in PD. However, clinicians and researchers should consider avoiding bolus holding during swallowing evaluations if attempting to assess RSC behaviors that are most typical for the examinee.

The Relationship Between Speech Characteristics and Motor Subtypes of Parkinson's Disease

2020 ◽  
Vol 29 (4) ◽  
pp. 2145-2154
Author(s):  
Katherine A. Brown ◽  
Kristie A. Spencer
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Rating Scale ◽  
Pause Duration ◽  
Speech Sample ◽  
Frequency Range ◽  
Speech Characteristics ◽  
Disease Rating ◽  
Cepstral Peak Prominence ◽  
The Relationship

Purpose The aim of this study was to examine whether acoustic dysarthria characteristics align with overall motor profile in individuals with Parkinson's disease (PD). Potential speech differences between tremor-dominant and non–tremor-dominant subtypes are theoretically motivated but empirically inconclusive. Method Twenty-seven individuals with dysarthria from PD provided a contextual speech sample. Participants were grouped into non–tremor-dominant ( n = 12) and tremor-dominant ( n = 15) motor subtypes according to the Unified Parkinson Disease Rating Scale. Dependent speech variables included fundamental frequency range, average pause duration, cepstral peak prominence, stuttering dysfluencies, and maze dysfluencies. Results There were no significant differences between the speech of the tremor-dominant and non–tremor-dominant groups. High within-group variability existed across parameters and motor subtypes. Conclusion Speech characteristics across the areas of phonation, prosody, and fluency did not differ appreciably between PD motor subtypes.

Effect of camptocormia on lung volumes in Parkinson's disease

2013 ◽  
Vol 187 (2) ◽  
pp. 164-166 ◽  
Author(s):  
Paolo Marinelli ◽  
Carlo Colosimo ◽  
Alessandro Maria Ferrazza ◽  
Flavio Di Stasio ◽  
Giovanni Fabbrini ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Lung Volumes

Respiratory Function in Parkinson's Subjects Exhibiting a Perceptible Speech Deficit

1989 ◽  
Vol 54 (4) ◽  
pp. 610-626 ◽  
Author(s):  
Bruce E. Murdoch ◽  
Helen J. Chenery ◽  
Simon Bowler ◽  
John C. L. Ingram
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Chest Wall ◽  
Respiratory Function ◽  
Neuromuscular Function ◽  
Lung Volumes ◽  
Normal Limits ◽  
Essentially Normal ◽  
Syllable Repetition ◽  
Age And Sex

The respiratory abilities of a group of 19 speech-disordered subjects with idiopathic Parkinson's disease were assessed using both spirometric and kinematic techniques and compared to those of a group of 19 nonneurologically impaired controls matched for age and sex. Results of the spirometric assessment showed that only a minority of the Parkinson's subjects had lung volumes and capacities outside normal limits. Consequently in the majority of eases, the speech disorder could not be related to any abnormality in lung function determined spirometrically. Chest wall dynamics during both conversation and reading were essentially normal in all cases. Approximately half of the Parkinson's subjects, however, exhibited irregularities in their chest wall movements while performing vowel prolongation and syllable repetition tasks. The same irregularities were not present in the chest wall movements exhibited by the control subjects, suggesting that their presence was in some way related to the Parkinson's disease. Results are discussed in terms of the effects of Parkinson's disease on neuromuscular function.

scholarly journals Acoustic and Perceptual Consequences of Speech Cues for Mandarin Speakers With Parkinson's Disease

2019 ◽  
Vol 28 (2) ◽  
pp. 521-535
Author(s):  
Sih-Chiao Hsu ◽  
Megan J. McAuliffe ◽  
Peiyi Lin ◽  
Ruey-Meei Wu ◽  
Erika S. Levy
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Scale Effects ◽  
Speech Rate ◽  
Statistical Significance ◽  
Pause Duration ◽  
Articulation Rate ◽  
Slow Condition ◽  
Speech Cues ◽  
Mandarin Speakers

PurposeThis study investigated the effects of cueing for increased loudness and reduced speech rate on scaled intelligibility and acoustics of speech produced by Mandarin speakers with hypokinetic dysarthria due to Parkinson's disease (PD).MethodEleven speakers with PD read passages in habitual, loud, and slow speaking conditions. Fifteen listeners rated ease of understanding (EOU) of the speech samples on a visual analog scale. Effects of the cues on EOU, vocal loudness, pitch range, pause duration and frequency, articulation rate, and vowel space, as well as relationships between EOU gains and acoustic features, were analyzed.ResultsEOU increased significantly in the loud condition only. The loud cue resulted in increased intensity, and the slow cue resulted both in reduced articulation rate and increased pause frequency. In the loud condition, EOU increased significantly as intensity increased and vowel centralization decreased. In the slow condition, EOU tended to increase as intensity increased and vowel centralization decreased but did not reach statistical significance.ConclusionCueing for loud speech may yield greater EOU gains than cueing for slow speech in Mandarin speakers with PD. Theoretical and clinical implications are discussed, although further investigations with more participants and a larger range of dysarthria severity are warranted.

Respiratory–Swallow Coordination Training and Voluntary Cough Skill Training: A Single-Subject Treatment Study in a Person With Parkinson's Disease

2020 ◽  
Vol 63 (2) ◽  
pp. 472-486 ◽  
Author(s):  
James A. Curtis ◽  
Avery E. Dakin ◽  
Michelle S. Troche
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Skill Training ◽  
Effect Sizes ◽  
Single Subject ◽  
Voluntary Cough ◽  
Respiratory Inductive Plethysmography ◽  
Standard Mean Difference ◽  
Coordination Training ◽  
Future Work

Purpose Airway protective disorders are common in Parkinson's disease (PD), yet effective methods to rehabilitate these life-threatening impairments are limited. This study examined the effects of two skill-based treatments aimed at improving swallowing and cough in a severely dysphagic person with PD: respiratory–swallow coordination training (RSCT) and voluntary cough skill training (VCST). It was hypothesized that (a) RSCT would improve respiratory–swallow coordination and swallowing safety and efficiency and (b) VCST would improve reflex and voluntary cough effectiveness. Method An 81-year-old man with midstage PD and severe dysphagia was recruited for study participation. The study utilized a multiple-baseline ABACA experimental design with a 2-month delayed retention assessment. Measures of respiratory–swallow coordination, swallowing safety and efficiency, and cough effectiveness were collected at each assessment using respiratory inductive plethysmography, flexible endoscopic evaluations of swallowing, and spirometry. Data were analyzed descriptively using baseline corrected tau and standard mean difference effect sizes ( d ). Results Large effect sizes were observed immediately following RSCT for respiratory–swallow coordination ( d = 9.17), penetration–aspiration ( d = 12.88), vallecular residue ( d = 1.75), piriform residue ( d = 4.15), and overall dysphagia severity ( d = 1.83). Large effect sizes were also observed immediately following VCST for single voluntary cough ( d = 4.30), sequential voluntary cough ( d = 3.28), and reflex cough ( d = 5.58). Improvements were maintained 2 months later for all outcome measures except single voluntary cough. Discussion This is the first study to examine the effects of RSCT and VCST in a person with PD. Robust improvements in respiratory–swallow coordination and swallowing safety and efficiency were achieved following four sessions of RSCT, and significant improvements in reflex and voluntary cough strength were seen following four sessions of VCST. Future work is needed to study these treatments in larger cohorts of people with PD.

Analysis of respiratory movements in a mouse model of late Parkinson’s disease submitted to stress

2018 ◽  
Vol 251 ◽  
pp. 50-56 ◽  
Author(s):  
P.S. de Campos ◽  
L.R.S.M. Kawamura ◽  
K. Hasegawa ◽  
Y. Kumei ◽  
J.L. Zeredo
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Mouse Model ◽  
Respiratory Movements

Evaluation of Efferent Auditory System and Hearing Quality in Parkinson's Disease: Is the Difficulty in Speech Understanding in Complex Listening Conditions Related to Neural Degeneration or Aging?

2020 ◽  
pp. 1-9
Author(s):  
Nuriye Yıldırım Gökay ◽  
Bülent Gündüz ◽  
Fatih Söke ◽  
Recep Karamert
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Auditory System ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Auditory Pathway ◽  
Normal Hearing ◽  
System Function ◽  
Distortion Product

Purpose The effects of neurological diseases on the auditory system have been a notable issue for investigators because the auditory pathway is closely associated with neural systems. The purposes of this study are to evaluate the efferent auditory system function and hearing quality in Parkinson's disease (PD) and to compare the findings with age-matched individuals without PD to present a perspective on aging. Method The study included 35 individuals with PD (mean age of 48.50 ± 8.00 years) and 35 normal-hearing peers (mean age of 49 ± 10 years). The following tests were administered for all participants: the first section of the Speech, Spatial and Qualities of Hearing Scale; pure-tone audiometry, speech audiometry, tympanometry, and acoustic reflexes; and distortion product otoacoustic emissions (DPOAEs) and contralateral suppression of DPOAEs. SPSS Version 25 was used for statistical analyses, and values of p < .05 were considered statistically significant. Results There were no statistically significant differences in the pure-tone audiometry thresholds and DPOAE responses between the individuals with PD and their normal-hearing peers ( p = .732). However, statistically significant differences were found between the groups in suppression levels of DPOAEs and hearing quality ( p < .05). In addition, a statistically significant and positive correlation was found between the amount of suppression at some frequencies and the Speech, Spatial and Qualities of Hearing Scale scores. Conclusions This study indicates that medial olivocochlear efferent system function and the hearing quality of individuals with PD were affected adversely due to the results of PD pathophysiology on the hearing system. For optimal intervention and follow-up, tasks related to hearing quality in daily life can also be added to therapies for PD.

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