Long-term effects of nitrous oxide anaesthesia on laboratory and clinical parameters in elderly Omani patients: a randomized double-blind study

AbstractLittle is known about long-term effects of homeopathic treatment. Following a double-blind, placebo controlled trial of classical homeopathy in chronic headaches, we conducted a 1-year observational study of 18 patients following the double-blind phase, and a complete follow-up study of all trial participants. Eighteen patients received free treatment for daily diary data (frequency, intensity, duration of headaches) over the course of 1 y. All patients enrolled in the double-blind study were sent a 6-week headache diary, a follow-up questionnaire, a personality inventory and a complaint list. Eighty-seven, of the original 98 patients enrolled returned questionnaires, 81 returned diaries. There was no additional change from the end of the trial to the one-year follow-up. The improvement seen at the end of the 12-week trial was stable after 1 y. No differential effects according to treatment after the trial could be seen. Patients with no treatment following the trial had the most improvement after 1 y. Five of 18 patients can be counted responders according to ARIMA analysis of single-case time-series. Patients with double diagnoses and longer treatment duration tended to have clearer improvements than the rest of the patients. Approximately 30% of patients in homeopathic treatment will benefit after 1 y of treatment. There is no indication of a specific, or of a delayed effect of homeopathy.

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THE EFFECT OF PROMAZINE ON THE ACTIVITY LEVEL OF RETARDED CHILDREN

PEDIATRICS ◽

10.1542/peds.33.2.271 ◽

1964 ◽

Vol 33 (2) ◽

pp. 271-275

Author(s):

Jerome L. Schulman ◽

Sister Mary Clarinda

Keyword(s):

Activity Level ◽

Blind Study ◽

Double Blind Study ◽

Night Time ◽

Double Blind ◽

Time Activity ◽

Drug Levels ◽

Daytime Activity ◽

Dose Levels

Promazine was administered to six hyperactive retarded boys in a long-term double-blind study. There were four dose levels —40, 60, 80, and 160 mg per day. The effect on activity level was measured with actometers. There was no effect on daytime activity when the placebo and drug levels were compared. There was a significant but clinically unimportant effect on night time activity.

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Treatment of Alzheimer's disease with short- and long-term oral THA and lecithin: a double-blind study

American Journal of Psychiatry ◽

10.1176/ajp.147.2.239 ◽

1990 ◽

Vol 147 (2) ◽

pp. 239-242 ◽

Cited By ~ 40

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Blind Study ◽

Double Blind Study ◽

Double Blind ◽

Short And Long Term

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Effect of a Combination of Intranasal Ketorolac and Nitrous Oxide on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study

Journal of Endodontics ◽

10.1016/j.joen.2017.09.011 ◽

2018 ◽

Vol 44 (1) ◽

pp. 9-13 ◽

Cited By ~ 6

Author(s):

Daniel Stentz ◽

Melissa Drum ◽

Al Reader ◽

John Nusstein ◽

Sara Fowler ◽

...

Keyword(s):

Nitrous Oxide ◽

Nerve Block ◽

Inferior Alveolar Nerve ◽

Blind Study ◽

Double Blind Study ◽

Inferior Alveolar Nerve Block ◽

Double Blind ◽

Irreversible Pulpitis

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Acute efects of the Paulinia cupana, "Guaraná" on the cognition of normal volunteers

Sao Paulo Medical Journal ◽

10.1590/s1516-31801994000300007 ◽

1994 ◽

Vol 112 (3) ◽

pp. 607-611 ◽

Cited By ~ 16

Author(s):

José Carlos Fernandes Galduróz ◽

Elisaldo de Araújo Carlini

Keyword(s):

Blind Study ◽

Double Blind Study ◽

Acute Effects ◽

Double Blind ◽

Normal Volunteers ◽

Term Basis

The authors studied the acute effects of "Guaraná", when compared to caffeine and placebo, (double blind study) on cognition, anxiety and sleep in 30 normal volunteers. Although results were negative it cannot be concluded that "Guaraná" is harmless. Other studies shall be undertaken, administering "Guaraná" on a long term basis, as popularly proclaimed.

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