Changes in Rat Serum Corticosterone After Treatment with Metabotropic Glutamate Receptor Agonists or Antagonists

2001 ◽  
Vol 13 (8) ◽  
pp. 670-677 ◽  
Author(s):  
M. P. Johnson ◽  
G. Kelly ◽  
M. Chamberlain
2008 ◽  
Vol 192 (2) ◽  
pp. 86-87 ◽  
Author(s):  
Paul J. Harrison

SummaryA drug acting at metabotropic glutamate receptors has recently been reported to be an effective antipsychotic, breaking the rule that only dopamine receptor-blocking drugs have this property. The finding complements accumulating evidence that glutamatergic abnormalities are important in the pathophysiology of schizophrenia.


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