The 'common mole' from the point of view of digital dermoscopy analysis: subjective vs. objective evaluation of easy pigmented skin lesions

2003 ◽  
Vol 17 (1) ◽  
pp. 28-33 ◽  
Author(s):  
M Burroni ◽  
P Rubegni ◽  
G Dell'eva ◽  
S Santini ◽  
R Perotti ◽  
...  
Keyword(s):  
Objective Evaluation ◽  
Skin Lesions ◽  
Point Of View ◽  
The Common ◽  
Pigmented Skin Lesions ◽  
Digital Dermoscopy

Dermoscopy and Digital Dermoscopy Analysis of Palmoplantar ‘Equivocal’ Pigmented Skin Lesions in Caucasians

Dermatology ◽  
2012 ◽  
Vol 225 (3) ◽  
pp. 248-255 ◽  
Author(s):  
P. Rubegni ◽  
G. Cevenini ◽  
N. Nami ◽  
G. Argenziano ◽  
T. Saida ◽  
...  
Keyword(s):  
Skin Lesions ◽  
Pigmented Skin Lesions ◽  
Digital Dermoscopy

Digital dermoscopy analysis of atypical pigmented skin lesions: a stepwise logistic discriminant analysis approach

2002 ◽  
Vol 8 (4) ◽  
pp. 276-281 ◽  
Author(s):  
P. Rubegni ◽  
G. Cevenini ◽  
M. Burroni ◽  
G. Dell'Eva ◽  
P. Sbano ◽  
...  
Keyword(s):  
Discriminant Analysis ◽  
Skin Lesions ◽  
Analysis Approach ◽  
Pigmented Skin Lesions ◽  
Digital Dermoscopy

The Role of Dermoscopy and Digital Dermoscopy Analysis in the Diagnosis of Pigmented Skin Lesions

2005 ◽  
Vol 141 (11) ◽  
Author(s):  
Pietro Rubegni ◽  
Marco Burroni ◽  
Andrea Andreassi ◽  
Michele Fimiani
Keyword(s):  
Skin Lesions ◽  
Pigmented Skin Lesions ◽  
Digital Dermoscopy

Evaluation Of The Functional Of Space-Planning Arrangement Of A Building

2019 ◽  
pp. 4-9
Keyword(s):  
Numerical Simulation ◽  
Life Cycle ◽  
Initial Data ◽  
Objective Assessment ◽  
Objective Evaluation ◽  
Point Of View ◽  
Shopping Centers ◽  
Space Planning ◽  
Planning Decisions ◽  
The Cost

The article focuses on the problem of the lack of objective evaluation of space-planning arrangement of buildings as a creative approach of the architect to the performing of functional tasks by the object. It is proposed to create a methodology for assessing the functional of space-planning solutions of buildings on the basis of numerical simulation of functional processes using the theory of human flows. There is a description of the prospects of using this method, which makes it possible to increase the coefficient of compactness, materials and works saving, more efficient use of space, reduce the cost of the life cycle of the building, save human forces and time to implement the functional of the building. The necessary initial data for modeling on the example of shopping and shopping-entertainment centers are considered. There are three main tasks for algorithmization of the functional of shopping centers. The conclusion is made about necessity of development of a method for objective assessment of buildings from the point of view of ergonomics of space-planning decisions based on the study of human behavior in buildings of different purposes.

COVID-19: a Great Mime or a Trigger Event of Autoimmune Manifestations?

2020 ◽  
Vol 16 ◽  
Author(s):  
Maria Celeste Fatone
Keyword(s):  
Autoimmune Diseases ◽  
Systemic Vasculitis ◽  
Skin Lesions ◽  
Endothelial Damage ◽  
Direct Role ◽  
Acute Interstitial Pneumonia ◽  
Trigger Event ◽  
The Common ◽  
Microvascular Inflammation ◽  
Autoimmune Phenomena

: Viruses can induce autoimmune diseases, in addition to genetic predisposition and environmental factors. Particularly, coronaviruses are mentioned among the viruses implicated in autoimmunity. Today, the world's greatest threat derives from the pandemic of a new human coronavirus, called “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2), the responsible agent of coronavirus disease 2019 (COVID-19). COVID-19 originated in Wuhan, the capital of Hubei, China in December 2019 and, to date, has spread to at least 187 countries. This review focuses on autoimmune manifestations described during COVID-19, including pro-thrombothic state associated to antiphospholipid antibodies (aPL), acute interstitial pneumonia, macrophage activation syndrome, lymphocytopenia, systemic vasculitis, and autoimmune skin lesions. This offers the opportunity to highlight the pathogenetic mechanisms common to COVID19 and several autoimmune diseases, in order to identify new therapeutic targets. In a supposed preliminary pathogenetic model, SARS-CoV-2 plays a direct role in triggering widespread microthrombosis and microvascular inflammation, because it is able to induce transient aPL, endothelial damage and complement activation at the same time. Hence, endothelium might represent the common pathway in which autoimmunity and infection converge. In addition, autoimmune phenomena in COVID-19 can be explained by regulatory T cells impairment and cytokines cascade.

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