Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain

2002 ◽  
Vol 81 (2) ◽  
pp. 257-269 ◽  
Author(s):  
G. Banisadr ◽  
F. Quéraud-Lesaux ◽  
M. C. Boutterin ◽  
D. Pélaprat ◽  
B. Zalc ◽  
...  
Keyword(s):  
Rat Brain ◽  
Chemokine Receptors ◽  
Functional Role ◽  
Cellular Localization ◽  
Adult Rat ◽  
Adult Rat Brain

Regional and cellular localization of the CXCl12/SDF-1 chemokine receptor CXCR7 in the developing and adult rat brain

2008 ◽  
Vol 510 (2) ◽  
pp. 207-220 ◽  
Author(s):  
Bastian Schönemeier ◽  
Angela Kolodziej ◽  
Stefan Schulz ◽  
Stefan Jacobs ◽  
Volker Hoellt ◽  
...  
Keyword(s):  
Rat Brain ◽  
Chemokine Receptor ◽  
Cellular Localization ◽  
Adult Rat ◽  
Adult Rat Brain

The neuroprotective role of l-cysteine towards the effects of short-term exposure to lanthanum on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase

BioMetals ◽  
2008 ◽  
Vol 22 (2) ◽  
pp. 329-335 ◽  
Author(s):  
Charis Liapi ◽  
Apostolos Zarros ◽  
Stamatios Theocharis ◽  
Hussam Al-Humadi ◽  
Foteini Anifantaki ◽  
...  
Keyword(s):  
Rat Brain ◽  
Antioxidant Status ◽  
Short Term ◽  
Adult Rat ◽  
Short Term Exposure ◽  
Adult Rat Brain

Antipsychotics promote GABAergic interneuron genesis in the adult rat brain: Role of heat-shock protein production

2017 ◽  
Vol 92 ◽  
pp. 108-118 ◽  
Author(s):  
Hiroo Kaneta ◽  
Wataru Ukai ◽  
Hanako Tsujino ◽  
Kengo Furuse ◽  
Yoshiyasu Kigawa ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Rat Brain ◽  
Protein Production ◽  
Gabaergic Interneuron ◽  
Adult Rat ◽  
Adult Rat Brain

scholarly journals Acetoacetate metabolism in rat brain. Development of acetoacetyl-coenzyme A deacylase and 3-hydroxy-3-methylglutaryl-coenzyme A synthase

1978 ◽  
Vol 176 (3) ◽  
pp. 951-958 ◽  
Author(s):  
T B Patel ◽  
J B Clark
Keyword(s):  
Rat Brain ◽  
Coenzyme A ◽  
Substrate Inhibition ◽  
Kinetic Studies ◽  
Developmental Studies ◽  
Mitochondrial Preparation ◽  
Adult Rat ◽  
Total Brain ◽  
Adult Rat Brain

1. Data are provided that indicate that the rat brain acetoacetyl-CoA deacylase is almost exclusively mitochondrial. Developmental studies show that this enzyme more than doubles its activity during suckling (0–21 days) and then maintains this activity in adults (approx. 1.1 units/g wet wt.). 2. Kinetic studies (on the acetoacetyl-CoA deacylase) in a purified brain mitochondrial preparation give a Vmax. of 47 nmol/min per mg of protein, and a Km for acetoacetyl-CoA of 5.2 micron and are compatible with substrate inhibition by acetoacetyl-CoA above concentrations of 47 micron. 3. The total brain 3-hydroxy-3-methyl-glutaryl-CoA synthase remains constant in the developing and adult rat brain (approx. 1.2 units/g wet wt.). This enzyme is located in both the mitochondrial and cytosolic fractions. During suckling (0–21 days) the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase represents approx. one-third of the total, but this increases markedly to about 60% of the total in the adult. The cytosolic enzyme correspondingly falls to approx. 40% of the total. 4. The role of the acetoacetyl-CoA deacylase in providing cytosolic acetoacetate for biosynthetic activities in the developing brain is discussed.

The role of astroglia in Pb-exposed adult rat brain with respect to glutamate toxicity

Toxicology ◽  
2005 ◽  
Vol 212 (2-3) ◽  
pp. 185-194 ◽  
Author(s):  
Lidia Strużyńska ◽  
Małgorzata Chalimoniuk ◽  
Grzegorz Sulkowski
Keyword(s):  
Rat Brain ◽  
Glutamate Toxicity ◽  
Adult Rat ◽  
Adult Rat Brain
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