Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2003.02289.x ◽

2004 ◽

Vol 89 (1) ◽

pp. 64-72 ◽

Author(s):

Hideyuki Takeuchi ◽

Jun-ichi Niwa ◽

Nozomi Hishikawa ◽

Shinsuke Ishigaki ◽

Fumiaki Tanaka ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Neuronal Cell ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lateral Sclerosis

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Mitochondrial Localization of Mutant Superoxide Dismutase 1 Triggers Caspase-dependent Cell Death in a Cellular Model of Familial Amyotrophic Lateral Sclerosis

Journal of Biological Chemistry ◽

10.1074/jbc.m209356200 ◽

2002 ◽

Vol 277 (52) ◽

pp. 50966-50972 ◽

Author(s):

Hideyuki Takeuchi ◽

Yasushi Kobayashi ◽

Shinsuke Ishigaki ◽

Manabu Doyu ◽

Gen Sobue

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Familial Amyotrophic Lateral Sclerosis ◽

Cellular Model ◽

Superoxide Dismutase 1 ◽

Mitochondrial Localization ◽

Dependent Cell ◽

Lateral Sclerosis

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Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis.

Journal of Biological Chemistry ◽

10.1074/jbc.a116.209356 ◽

2016 ◽

Vol 291 (42) ◽

pp. 22341-22343

Author(s):

Hideyuki Takeuchi ◽

Yasushi Kobayashi ◽

Shinsuke Ishigaki ◽

Manabu Doyu ◽

Gen Sobue

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Familial Amyotrophic Lateral Sclerosis ◽

Cellular Model ◽

Superoxide Dismutase 1 ◽

Mitochondrial Localization ◽

Dependent Cell ◽

Lateral Sclerosis

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Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

Neuropathology ◽

10.1046/j.1440-1789.2001.00361.x ◽

2001 ◽

Vol 21 (1) ◽

pp. 82-92 ◽

Author(s):

Noriyuki Shibata

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lateral Sclerosis

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New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: Inclusions containing SOD1 in neurons and astrocytes

Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders ◽

10.1080/14660820050515160 ◽

2000 ◽

Vol 1 (3) ◽

pp. 163-184 ◽

Author(s):

Shinsuke Kato ◽

Miki Takikawa ◽

Kenji Nakashima ◽

Asao Hirano ◽

Don W Cleveland ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Gene Mutations ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Sod1 Gene ◽

Lateral Sclerosis

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Neuropathology of familial amyotrophic lateral sclerosis patients with superoxide dismutase 1 gene mutation

Neuropathology ◽

10.1111/j.1440-1789.1998.tb00132.x ◽

1998 ◽

Vol 18 (4) ◽

pp. 363-369 ◽

Author(s):

Asao Hirano

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Gene Mutation ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lateral Sclerosis

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MRI detects early hindlimb muscle atrophy in Gly93Ala superoxide dismutase-1 (G93A SOD1) transgenic mice, an animal model of familial amyotrophic lateral sclerosis

NMR in Biomedicine ◽

10.1002/nbm.861 ◽

2004 ◽

Vol 17 (1) ◽

pp. 28-32 ◽

Author(s):

Keith J. Brooks ◽

Mark D. W. Hill ◽

Paul D. Hockings ◽

David G. Reid

Keyword(s):

Animal Model ◽

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Transgenic Mice ◽

Muscle Atrophy ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Hindlimb Muscle ◽

G93a Sod1 ◽

Lateral Sclerosis

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Familial Amyotrophic Lateral Sclerosis with a Novel G85S Mutation of Superoxide Dismutase 1 Gene: Clinical Features of Lower Motor Neuron Disease

Internal Medicine ◽

10.2169/internalmedicine.49.2720 ◽

2010 ◽

Vol 49 (2) ◽

pp. 183-186 ◽

Author(s):

Takanori Takazawa ◽

Ken Ikeda ◽

Takehisa Hirayama ◽

Kiyokazu Kawabe ◽

Yoshikazu Nakamura ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Motor Neuron Disease ◽

Clinical Features ◽

Lower Motor Neuron ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lower Motor Neuron Disease ◽

Lateral Sclerosis

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Stability of Mutant Superoxide Dismutase-1 Associated with Familial Amyotrophic Lateral Sclerosis Determines the Manner of Copper Release and Induction of Thioredoxin in Erythrocytes

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1998.8265 ◽

1998 ◽

Vol 244 (2) ◽

pp. 605

Author(s):

Yasuko Ogawa ◽

Hiroaki Kosaka ◽

Toyohumi Nakanishi ◽

Akira Shimizu ◽

Nagato Ohoi ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Copper Release ◽

Lateral Sclerosis

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Variation in the Biochemical/Biophysical Properties of Mutant Superoxide Dismutase 1 Enzymes and the Rate of Disease Progression in Familial Amyotrophic Lateral Sclerosis Kindreds

Human Molecular Genetics ◽

10.1093/hmg/8.8.1451 ◽

1999 ◽

Vol 8 (8) ◽

pp. 1451-1460 ◽

Author(s):

T. Ratovitski ◽

L. B. Corson ◽

J. Strain ◽

P. Wong ◽

D. W. Cleveland ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Disease Progression ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Biophysical Properties ◽

Lateral Sclerosis

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Improving Binding Specificity of Pharmacological Chaperones That Target Mutant Superoxide Dismutase-1 Linked to Familial Amyotrophic Lateral Sclerosis Using Computational Methods

Journal of Medicinal Chemistry ◽

10.1021/jm901062p ◽

2010 ◽

Vol 53 (7) ◽

pp. 2709-2718 ◽

Author(s):

Richard J. Nowak ◽

Gregory D. Cuny ◽

Sungwoon Choi ◽

Peter T. Lansbury ◽

Soumya S. Ray

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Computational Methods ◽

Binding Specificity ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Pharmacological Chaperones ◽

Lateral Sclerosis

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