scholarly journals Control of sustainable management according to multilevel combinatorics of homeostatic mechanisms

2021 ◽  
Vol 255 ◽  
pp. 01029
Author(s):  
Victoriia Mykytenko ◽  
Nataliia Sheludko
Keyword(s):  
Sustainable Management ◽  
Specific Effect ◽  
Structural Hierarchy ◽  
Cognitive Information ◽  
Management Concept ◽  
Adequate Design ◽  
Homeostatic Mechanisms

The article aims to develop the methodological base for study and substantiation of homeostatic mechanisms of control of stability of managing systems in the conditions which is implemented according to the sustainable management concept. The article describes features of main types of homeostasis of managing systems (evolutionary, structural, resistant, system homeostasis), their hierarchical closed interrelation and inherent specific and predictive administrative properties. The following is herein substantiated: conditions of homeostasis generation and realization of specific effect of mechanisms and, respectively, regulators of adaptation of managing systems to external and internal transformations; directions and methods to form resistant, to institutional and resource restrictions, complementary managing complexes. The article states that the combinatorics of homeostasis controls includes stabilizing, inertial, adaptation, organizational and economic, kinematic, cybernetic, alarm, cognitive information, reparative, regenerative and other types of controls. It emphasizes that the complex of mechanisms to ensure self-regulating properties of systems must be focused on support of their adaptation abilities to external and internal transformations. Taking into account four-level structural hierarchy of homeostatic properties, the article substantiates the possibility of ensuring adequate design of regulators for their consolidation according to priority objects of tools and events localization.

Towards a sustainable management concept for ecosystem services of the Pantanal wetland

2008 ◽  
Vol 8 (2-4) ◽  
pp. 115-138 ◽  
Author(s):  
Karl M. Wantzen ◽  
Cátia Nunes da Cunha ◽  
Wolfgang J. Junk ◽  
Pierre Girard ◽  
Onélia Carmen Rossetto ◽  
...  
Keyword(s):  
Ecosystem Services ◽  
Sustainable Management ◽  
Management Concept ◽  
Pantanal Wetland

scholarly journals Participatory rural appraisal of ecosystem services of wetlands in the Amazonian Piedmont of Colombia: elements for a sustainable management concept

2013 ◽  
Vol 22 (4) ◽  
pp. 343-361 ◽  
Author(s):  
Luisa Fernanda Ricaurte ◽  
Karl Matthias Wantzen ◽  
Edwin Agudelo ◽  
Bernardo Betancourt ◽  
Jukka Jokela
Keyword(s):  
Ecosystem Services ◽  
Sustainable Management ◽  
Participatory Rural Appraisal ◽  
Management Concept ◽  
Rural Appraisal

The Effect of Vitamin A on the Intermittent Nitrogen Dioxide Gas Exposure in Hamsters

1976 ◽  
Vol 34 ◽  
pp. 176-177
Author(s):  
J.C.S. Kim ◽  
M.G. Jourden ◽  
E.S. Carlisle
Keyword(s):  
Electron Microscopy ◽  
Vitamin A ◽  
Nitrogen Dioxide ◽  
Chronic Exposure ◽  
Light And Electron Microscopy ◽  
Specific Effect ◽  
Deficient Diet ◽  
Intermittent Exposure ◽  
Hypovitaminosis A ◽  
Gas Exposure

Chronic exposure to nitrogen dioxide in rodents has shown that injury reaches a maximum after 24 hours, and a reparative adaptive phase follows (1). Damage occurring in the terminal bronchioles and proximal portions of the alveolar ducts in rats has been extensively studied by both light and electron microscopy (1).The present study was undertaken to compare the response of lung tissue to intermittent exposure to 10 ppm of nitrogen dioxide gas for 4 hours per week, while the hamsters were on a vitamin A deficient diet. Ultrastructural observations made from lung tissues obtained from non-gas exposed, hypovitaminosis A animals and gas exposed animals fed a regular commercially prepared diet have been compared to elucidate the specific effect of vitamin A on nitrogen dioxide gas exposure. The interaction occurring between vitamin A and nitrogen dioxide gas has not previously been investigated.

Platelet-Bound Prekallikrein Promotes Pro-Urokinase-Induced Clot Lysis: A Mechanism for Targeting the Factor XII Dependent Intrinsic Pathway of Fibrinolysis

1994 ◽  
Vol 71 (03) ◽  
pp. 347-352 ◽  
Author(s):  
Jean-Pierre Loza ◽  
Victor Gurewich ◽  
Michael Johnstone ◽  
Ralph Pannell
Keyword(s):  
Platelet Rich Plasma ◽  
Specific Inhibitor ◽  
Specific Effect ◽  
Clot Lysis ◽  
Factor Xii ◽  
Intrinsic Pathway ◽  
Clot Retraction ◽  
Enzymatic Mechanism ◽  
Low Concentrations ◽  
Factor Xiia

SummaryClots formed from platelet rich plasma were found to be lysed more readily by low concentrations of pro-urokinase (pro-UK) than clots formed from platelet poor plasma. This was not a non-specific effect since the reverse occurred with tissue plasminogen activator. A mechanical explanation due to platelet-mediated clot retraction was excluded by experiments in which retraction was inhibited with cyto-chalasin B. Therefore, a platelet-mediated enzymatic mechanism was postulated to explain the promotion of fibrinolysis. Casein autography of isolated platelets revealed a ≈ 90 kDa band of activity which comigrated with plasma prekallikrein (PK)/kallikrein, a known activator of pro-UK. Furthermore, treatment of platelets with plasma PK activator (PPA), consisting essentially of factor XIIa, induced activation of pro-UK and of chromomgenic substrate for kallikrein (S-2302). This activity corresponded to approximately 40-200 pM kallikrein per 10 8 washed and gel filtered platelets per ml. The activation of pro-UK by PPA-pretreated platelets was dose-dependent and inhibited by soybean trypsin inhibitor but not by bdellin, a specific inhibitor of plasmin, nor by the corn inhibitor of factor XIIa. Kinetic analysis of pro-UK activation by kallikrein showed promotion of the reaction by platelets. The KM of the reaction was reduced by platelets by ≈ 7-fold, while the kcat was essentially unchanged. In conclusion, PK was shown to be tightly associated with platelets where it can be activated by factor XIIa during clotting. The activation of pro-UK by platelet-bound kallikrein provides an explanation for the observed platelet mediated promotion of pro-UK-induced clot lysis. Since pro-UK and plasminogen have also been shown to be associated with platelets, the present findings suggest a mechanism by which the factor Xlla-dependent intrinsic pathway of fibrinolysis can be localized and targeted to a thrombus.

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