scholarly journals Molecular characterization of Mycobacterium tuberculosis complex isolates from wild ungulates in south-central Spain

2005 ◽  
Vol 36 (1) ◽  
pp. 43-52 ◽  
Author(s):  
Christian Gortazar ◽  
Joaqu�n Vicente ◽  
Sofia Samper ◽  
Joseba M. Garrido ◽  
Isabel G. Fern�ndez-De-Mera ◽  
...  
2005 ◽  
Vol 43 (9) ◽  
pp. 4858-4861 ◽  
Author(s):  
M. Gazouli ◽  
J. Ikonomopoulos ◽  
A. Koundourakis ◽  
M. Bartos ◽  
I. Pavlik ◽  
...  

1997 ◽  
Vol 41 (7) ◽  
pp. 1601-1603 ◽  
Author(s):  
W H Haas ◽  
K Schilke ◽  
J Brand ◽  
B Amthor ◽  
K Weyer ◽  
...  

A sample of 124 isoniazid (INH)-resistant and 88 susceptible strains of Mycobacterium tuberculosis complex from south, central, and west Africa was analyzed by direct sequence analysis and PCR-restriction fragment length polymorphism analysis of their catalase-peroxidase (katG) genes. Point mutations at codon 315 were found in the genomes of 64% of INH-resistant strains, but no complete deletions were identified. Mutations at codon 463 were independent of INH resistance and were linked to the geographic origins of the strains.


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