Dual Phase Helical CT Versus Portal Venous Phase CT For the Detection of Colorectal Liver Metastases: Correlation with Intra-operative Sonography, Surgical and Pathological Findings

Abstract Background:The utility of dual-phase enhanced CT scan in distinguishing ganglioneuromas from lipid-poor adenomas has not been reported. We aimed to prospectively compare CT findings helpful in distinguishing adrenal ganglioneuromas from adrenal lipid-poor adenomas. Methods: We estimated the CT findings of 258 adrenal masses (42 ganglioneuromas, 216 lipid-poor adenomas) in 258 patients from July 2008 to July 2020 with ganglioneuromas and July 2016 to July 2020 with lipid-poor adenomas. The CT features between ganglioneuromas and lipid-poor adenomas were compared. Results:Significant differences were detected in CT value of unenhanced (CTU), CT value of arterial phase (CTA), CT value of venous phase (CTV), degree of enhancement in arterial phase (DEAP), degree of enhancement in portal venous phase (DEPP), age, tumor size [long diameter (LD), short diameter (SD), mean diameter (MD)], shape, calcification between the ganglioneuroma and lipid-poor adenoma groups (P < 0.05).The results of receiver operating characteristics (ROC) analyses showed that areas under ROC curves (AUC) of CTU, CTA and CTV were 0.713, 0.878, and 0.914, respectively. When the cut-off values were set at 22.5 HU, 51.5 HU, and 53.5 HU for CTU, CTA, and CTV, respectively the three parameters had a sensitivity of 46.8%, 67.6%, and 88.0% and a specificity of 100%, 100%, and 88.1% in distinguishing between ganglioneuromas and lipid-poor adenomas.Conclusion: Dual-phase enhanced abdominal CT can exhibit some of the primary imaging characteristics of ganglioneuromas and lipid-poor adenomas used to distinguish between these two entities.

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CT imaging of intrabiliary growth of colorectal liver metastases: a comparison of pathological findings of resected specimens

British Journal of Radiology ◽

10.1259/bjr.75.894.750497 ◽

2002 ◽

Vol 75 (894) ◽

pp. 497-501 ◽

Cited By ~ 32

Author(s):

K Okano ◽

J Yamamoto ◽

T Okabayashi ◽

Y Sugawara ◽

K Shimada ◽

...

Keyword(s):

Liver Metastases ◽

Colorectal Liver Metastases ◽

Ct Imaging ◽

Pathological Findings ◽

Intrabiliary Growth

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Hepatic parenchymal perfusion abnormalities after pancreaticobiliary surgery

Acta Radiologica ◽

10.1080/02841859809172200 ◽

1998 ◽

Vol 39 (3) ◽

pp. 304-308

Author(s):

K. Mitsuzaki ◽

Y. Yamashita ◽

I. Ogata ◽

T. Nishiharu ◽

J. Urata ◽

...

Keyword(s):

Malignant Tumors ◽

Equilibrium Phase ◽

Contrast Material ◽

Helical Ct ◽

Arterial Phase ◽

Perfusion Abnormality ◽

Portal Venous Phase ◽

Before And After ◽

Venous Phase ◽

One Year

Purpose: To evaluate perfusion abnormalities of the liver after pancreaticobiliary surgery Material and Methods: We retrospectively evaluated 128 patients with pancreaticobiliary malignant tumors who had been examined both before and after surgery by means of helical CT of the liver. An infusion of 3 ml/s of 60% nonionic contrast material was followed by helical CT of the liver in a sequential arterial phase, portal venous phase, and equilibrium phase Results: of 128 patients, we followed 97. In 21 patients (22%) we found 47 lesions with perfusion abnormalities that were detected 1–33 months (mean 6.6 months) after the operation. All patients were asymptomatic. The shape of each perfusion abnormality was characterized as geographic (n=23, 47%), wedgeshaped (n=21, 45%), or round (n=3, 83.8%). The abnormalities were seen in the arterial phase in 46 lesions (98%), in the portal venous phase in 18 lesions (38%), and in the equilibrium phase in 1 lesion (0.2%). In all lesions, the size either decreased spontaneously, or it remained unchanged for more than one year Conclusion: Perfusion abnormalities of the liver may occur in patients who undergo pancreaticobiliary surgery. This findings should not be confused with hypervascular metastases

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Evaluation of peripheral enhancement on contrast-enhanced CT and corresponding pathological findings in colorectal liver metastases after preoperative chemotherapy

10.1101/2021.10.27.21265582 ◽

2021 ◽

Author(s):

Akio Tamura ◽

Kazuyuki Ishida ◽

Misato Sone ◽

Kunihiro Yoshioka

Keyword(s):

Liver Metastases ◽

Preoperative Chemotherapy ◽

Colorectal Liver Metastases ◽

Pathological Findings ◽

Contrast Effects ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Group 2 ◽

Peripheral Enhancement ◽

Smooth Margin

Objective: To correlate peripheral enhancement on contrast-enhanced computed tomography (CE-CT) of post-chemotherapy colorectal liver metastases (CRLM) patients with the pathological findings. Methods: Forty-four patients with CRLM who underwent hepatic resection after preoperative chemotherapy between 2008 and 2013 were included. Two radiologists blinded to the histopathology findings performed a consensus categorization of the marginal contrast effects of CRLM on CE-CT as follows: Group 1, smooth margin without enhancement; Group 2, smooth margin with an enhanced rim; and Group 3, fuzzy margin with/without an enhanced rim. The Kruskal-Wallis test was used to compare the imaging findings with the histological findings. Results: The percentage of infarct-like necrosis was significantly higher in CRLM with smooth margins than in those with fuzzy margins (p<0.001, r=0.62). The percentage of viable cells was lowest in CRLM with smooth margins without enhancement (p<0.001, r=0.60). Conclusions: Our findings suggest that the type of necrosis is related to the nature of the margins, and the presence of residual cells are related to peripheral enhancement.

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