How Significant is Detection of Ductal Carcinoma In Situ in a Breast Screening Programme?

Objective Monitoring breast screening programmes is essential to ensure quality. BreastCheck, the national breast screening programme in the Republic of Ireland, commenced screening in 2000, with full national expansion in 2007, and digital mammography introduced in 2008. We aimed to review the performance of BreastCheck from 1 January 2004 to 31 December 2013. Methods Using the customised clinical and administrative database, performance indicator data were collected from BreastCheck and compared with programme and European guideline standards. Results Over the decade, 972,236 screening examinations were performed. Uptake initially rose following national expansion, but fell in the subsequent years to <70% in 2012–2013. Following the introduction of digital mammography, initial recall rates increased from 5.2% in 2004–2005 to 8.1% in 2012–2013. Subsequent recall rates remained within the target of <3%. On average, invasive cancer detection rates were 6.6/1000 for initial and 4.5/1000 for subsequent women. Small cancer detection rates were for <15 mm 43.4% (initial women) and 51.7% (subsequent) and for ≤10 mm 24.0% (initial) and 29.5% (subsequent). Ductal carcinoma in situ detection as a percentage of all cancers averaged 21.2% for initial and 20.0% for subsequent women. The majority were intermediate or high-grade ductal carcinoma in situ. The positive predictive value was 11.9% for initial and 21.8% for subsequent women. Standardized detection ratios remained above the programme target. Conclusion Revised indicators to reflect the digital mammography era are anticipated in revised European Guidelines on breast cancer screening.

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Screen-detected lobular carcinoma in situ (LCIS) of the breast: 166 cases within the National Health Service Breast Screening Programme (NHSBSP)

Breast Cancer Research ◽

10.1186/bcr839 ◽

2004 ◽

Vol 6 (S1) ◽

Author(s):

RKF Hogben ◽

MW Kissin ◽

C de Vries ◽

P Jackson ◽

C Kissin

Keyword(s):

National Health Service ◽

Health Service ◽

Carcinoma In Situ ◽

Breast Screening ◽

Screening Programme ◽

Lobular Carcinoma ◽

Lobular Carcinoma In Situ ◽

Breast Screening Programme ◽

National Health Service Breast

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Adenomyoepithelioma with Ductal Carcinoma In Situ: A Case Report and Review of the Literature

Case Reports in Surgery ◽

10.1155/2013/521417 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3 ◽

Cited By ~ 4

Author(s):

Sanjay Warrier ◽

Sang Hwang ◽

Martha Ghaly ◽

Alex Matthews

Keyword(s):

Case Report ◽

Literature Review ◽

Ductal Carcinoma In Situ ◽

Growth Pattern ◽

Carcinoma In Situ ◽

Breast Screening ◽

Ductal Carcinoma ◽

Review Of The Literature ◽

Microglandular Adenosis

Adenomyoepithelioma (AME) with microglandular adenosis-like growth pattern and superimposed ductal carcinoma in situ (DCIS) was identified in a 55-year-old female after biopsy of an atypical lesion identified through routine breast screening. A literature review reveals that this association has rarely been described.

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A review of needle core biopsy diagnosed radial scars in the Welsh Breast Screening Programme

Annals of The Royal College of Surgeons of England ◽

10.1308/003588411x12851639107953 ◽

2011 ◽

Vol 93 (2) ◽

pp. 123-126 ◽

Cited By ~ 26

Author(s):

G Osborn ◽

F Wilton ◽

G Stevens ◽

E Vaughan-Williams ◽

K Gower-Thomas

Keyword(s):

Core Biopsy ◽

Breast Screening ◽

Screening Programme ◽

Ductal Carcinoma ◽

Surgical Excision ◽

Excision Biopsy ◽

Needle Core Biopsy ◽

Breast Screening Programme ◽

Benign Biopsy

INTRODUCTION Radial scars are benign breast lesions; their appearance on mammography may, however, mimic carcinoma. Needle core biopsy is performed for pre-operative diagnosis and, currently in Wales, all lesions with benign biopsy results are surgically excised. We have reviewed all cases of needle core biopsy-diagnosed radial scars from the Welsh breast screening programme, Breast Test Wales (BTW), and investigated the outcome of radial scars based on histology from surgical excision in order to evaluate the appropriateness of the current management of these lesions in Wales. PATIENTS AND METHODS All needle core biopsy diagnosed radial scars were identified from the BTW screening database from the start of screening in 1989 until the end of 2007. RESULTS A total of 118 patients were diagnosed with radial scars on needle core biopsy; two patients had bilateral radial scars. Median patient age was 54 years (range, 49-68 years). Ninety-five lesions (79%) were thought to be pure radial scars on needle core biopsy; however, only 81 pure radial scars were identified on excision biopsy histology. Carcinoma was present in seven patients and ductal carcinoma in situ in nine patients at excision biopsy. In two patients, the cancers occurred in lesions reported as pure radial scars on needle core biopsy. Twenty-two lesions showed atypical ductal or lobular hyperplasia (ADH/ALH) or both on excision biopsy; 14 of these lesions were classed as pure radial scars by needle core biopsy. CONCLUSIONS All core biopsy diagnosed radial scars, presenting as screen detected abnormalities, should be excised due to their association with premalignant and malignant conditions.

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