URINARY BLADDER NECROSIS - AN EXTRAINTESTINAL MANIFESTATION OF INFLAMMATORY BOWEL DISEASE IN A PEDIATRIC PATIENT

2021 ◽  
Vol 160 (3) ◽  
pp. S23
Author(s):  
Nicholas Norris ◽  
Bruce Schlomer ◽  
Bhaskar Gurram
Keyword(s):  
Inflammatory Bowel Disease ◽  
Urinary Bladder ◽  
Pediatric Patient ◽  
Bowel Disease ◽  
Extraintestinal Manifestation ◽  
Bladder Necrosis ◽  
Inflammatory Bowel

scholarly journals The burden and management of anemia in Greek patients with inflammatory bowel disease: a retrospective, multicenter, observational study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kalliopi Foteinogiannopoulou ◽  
Konstantinos Karmiris ◽  
Georgios Axiaris ◽  
Magdalini Velegraki ◽  
Antonios Gklavas ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Clinical Laboratory ◽  
Real Life ◽  
Extraintestinal Manifestations ◽  
Extraintestinal Manifestation ◽  
Multicenter Observational Study ◽  
Treatment Data ◽  
Inflammatory Bowel ◽  
Anemia Treatment

Abstract Background Anemia is a common extraintestinal manifestation of Inflammatory Bowel Disease (IBD) affecting negatively the patients’ quality of life. The aim of this study was to determine the frequency and real-life management of anemia in IBD patients in Greece. Methods This study was conducted in 17 Greek IBD referral centers. Demographic, clinical, laboratory, IBD and anemia treatment data were collected and analyzed retrospectively. Results A total of 1394 IBD patients [560 ulcerative colitis (UC), 834 Crohn’s disease (CD)] were enrolled. Anemia at any time was reported in 687 (49.3%) patients of whom 413 (29.6%) had episodic and 274 (19.7%) had recurrent/persistent anemia. Anemia was diagnosed before IBD in 45 (6.5%), along with IBD in 269 (39.2%) and after IBD in 373 (54.3%) patients. In the multivariate analysis the presence of extraintestinal manifestations (p = 0.0008), IBD duration (p = 0.026), IBD related surgeries and hospitalizations (p = 0.026 and p = 0.004 accordingly) were risk factors of recurrent/persistent anemia. Serum ferritin was measured in 839 (60.2%) IBD patients. Among anemic patients, 535 (77.9%) received treatment. Iron supplementation was administered in 485 (90.6%) patients, oral in 142 (29.3%) and intravenous in 393 (81%). Conclusions The frequency of anemia in IBD patients, followed at Greek referral centers, is approximately 50%. Development of recurrent/persistent anemia may be observed in 20% of cases and is independently associated with the presence of extraintestinal manifestations, IBD duration, IBD related surgeries and hospitalizations. Anemia treatment is administered in up to $$4/5$$ 4 / 5 of anemia IBD patients with the majority of them receiving iron intravenously.

scholarly journals Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease

2014 ◽  
Vol 89 (6) ◽  
pp. 967-969 ◽  
Author(s):  
Yumi Cristina Komatsu ◽  
Gabriela Cunha Capareli ◽  
Maria Fernanda Feitosa de Camargo Boin ◽  
Rute Lellis ◽  
Thaís Helena Proença de Freitas ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Extraintestinal Manifestation ◽  
Inflammatory Bowel

Inflammatory Bowel Disease in the Pediatric Patient

2007 ◽  
Vol 87 (3) ◽  
pp. 643-658 ◽  
Author(s):  
Todd Ponsky ◽  
Anna Hindle ◽  
Anthony Sandler
Keyword(s):  
Inflammatory Bowel Disease ◽  
Pediatric Patient ◽  
Bowel Disease ◽  
Inflammatory Bowel

INFLAMMATORY BOWEL DISEASE IN THE PEDIATRIC PATIENT

1995 ◽  
Vol 24 (3) ◽  
pp. 613-632 ◽  
Author(s):  
Richard J. Grand ◽  
Jyoti Ramakrishna ◽  
Kathleen A. Calenda
Keyword(s):  
Inflammatory Bowel Disease ◽  
Pediatric Patient ◽  
Bowel Disease ◽  
Inflammatory Bowel

scholarly journals Cerebral Arterial Thrombosis in Ulcerative Colitis

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Giovanni Casella ◽  
Claudio Camillo Cortelezzi ◽  
DeLodovici Marialuisa ◽  
Princiotta Cariddi Lucia ◽  
Verrengia Elena Pinuccia ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Arterial Thrombosis ◽  
Sclerosing Cholangitis ◽  
International Literature ◽  
Extraintestinal Manifestation ◽  
Intraarterial Thrombolysis ◽  
Inflammatory Bowel ◽  
Cerebral Arterial Thrombosis

Thrombosis, mainly venous, is a rare and well-recognized extraintestinal manifestation of inflammatory bowel disease (IBD). We describe a 25-year-old Caucasian man affected by ulcerative colitis and sclerosing cholangitis with an episode of right middle cerebral arterial thrombosis resolved by intraarterial thrombolysis. We perform a brief review of the International Literature.

scholarly journals Renal involvement in paediatric inflammatory bowel disease

2019 ◽  
Author(s):  
Mohamed Mutalib
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Renal Involvement ◽  
Host Immune System ◽  
Inflammatory Disorder ◽  
Extraintestinal Manifestation ◽  
Metabolic Complications ◽  
Chronic Inflammatory Disorder ◽  
Renal Manifestation ◽  
Inflammatory Bowel

AbstractInflammatory bowel disease (IBD), which includes Crohn’s disease, ulcerative colitis and inflammatory bowel disease unclassified, is a chronic inflammatory disorder that predominantly affects the gastrointestinal (GI) tract and has a rising incidence in both children and adults. Symptoms are caused by inappropriate inflammatory response triggered by interaction between the environment, gut microbiome and host immune system in a genetically susceptible individual. Extranintestinal manifestations of IBD are common and can affect any body system outside the gut; they can precede or run parallel to GI inflammation. Renal involvement in IBD is uncommon and can be part of extraintestinal manifestation or metabolic complications of IBD. Many medications used to treat IBD can cause renal damage. Renal manifestation in children with IBD can range from asymptomatic biochemical abnormalities to variable stages of renal impairment with significant morbidity and even mortality burden.

scholarly journals High Prevalence of Ultrasound Verified Enthesitis in Patients With Inflammatory Bowel Disease With or Without Spondylarthritis

2021 ◽  
Vol 8 ◽  
Author(s):  
Rusmir Husic ◽  
Angelika Lackner ◽  
Patrizia Katharina Kump ◽  
Christoph Högenauer ◽  
Winfried Graninger ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Irritable Bowel Syndrome ◽  
Bowel Disease ◽  
Healthy Subjects ◽  
Ultrasound Examination ◽  
Clinical Signs ◽  
Extraintestinal Manifestation ◽  
High Prevalence ◽  
Inflammatory Bowel ◽  
Irritable Bowel

Background: Inflammatory bowel disease (IBD) is closely associated with spondylarthritis (SpA) and enthesitis, as an important feature of SpA, is a common extraintestinal manifestation of IBD. Enthesitis may be clinically silent in a high proportion of patients with IBD without clinical signs or a diagnosis of SpA.Objectives: The aim of this study was to compare the prevalence of ultrasound (US) verified enthesitis in IBD patients with and without SpA, with patients with irritable bowel syndrome (IBS) and healthy subjects (HC) serving as controls.Methods: IBD patients with or without SpA, patients with IBS and HC were prospectively recruited and clinically assessed. Ultrasound examination was performed at 14 entheses. The ultrasound abnormalities were scored according to the Madrid Ankylosing Spondylitis Enthesitis Index (MASEI).Results: We included 33 IBD patients without SpA, 14 IBD patients with SpA, 26 IBS patients and 18 HC. Higher MASEI scores were found in patients with IBD without SpA [median 21.0 range (8.0–53.0)] and IBD associated SpA [33.0 (8–50)] than in IBS patients [10.5 (0–42.0)-p < 0.001 for both comparison] and HC [12.0 (2.0–38.0)-p < 0.01]. PD, enthesophytes and erosions were more common in patients with IBD with or without SpA as compared to IBS patients and HC. IBD patients with SpA compared to IBD without SpA demonstrated significant higher prevalence of erosion and structural irregularity and consequently significant higher MASEI (p < 0.05 for all comparison).Conclusions: Ultrasound verified enthesitis is more common in patients with IBD with or without SpA as compared to patients with IBS or HC.

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