Neuroimaging of Acute Traumatic Brain Injury: Emphasis on Magnetic Resonance Imaging and Prognostic Factors

2014 ◽  
Vol 49 (1) ◽  
pp. 64-75 ◽  
Author(s):  
Ivan M. DeQuesada ◽  
Falgun H. Chokshi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Traumatic Brain Injury ◽  
Prognostic Factors ◽  
Brain Injury ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Acute Traumatic Brain Injury

Magnetic resonance imaging changes in the pituitary gland following acute traumatic brain injury

2007 ◽  
Vol 34 (3) ◽  
pp. 468-475 ◽  
Author(s):  
Balachandra Maiya ◽  
Virginia Newcombe ◽  
Jurgens Nortje ◽  
Peter Bradley ◽  
Francis Bernard ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Magnetic Resonance ◽  
Pituitary Gland ◽  
Resonance Imaging ◽  
Acute Traumatic Brain Injury

scholarly journals The Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Evaluation of Blood-Brain Barrier Disruption in Traumatic Brain Injury: What Is the Evidence?

2021 ◽  
Vol 11 (6) ◽  
pp. 775
Author(s):  
Sung-Suk Oh ◽  
Eun-Hee Lee ◽  
Jong-Hoon Kim ◽  
Young-Beom Seo ◽  
Yoo-Jin Choo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Magnetic Resonance ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Resonance Imaging ◽  
Dce Mri ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced

(1) Background: Blood brain barrier (BBB) disruption following traumatic brain injury (TBI) results in a secondary injury by facilitating the entry of neurotoxins to the brain parenchyma without filtration. In the current paper, we aimed to review previous dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) studies to evaluate the occurrence of BBB disruption after TBI. (2) Methods: In electronic databases (PubMed, Scopus, Embase, and the Cochrane Library), we searched for the following keywords: dynamic contrast-enhanced OR DCE AND brain injury. We included studies in which BBB disruption was evaluated in patients with TBI using DCE-MRI. (3) Results: Four articles were included in this review. To assess BBB disruption, linear fit, Tofts, extended Tofts, or Patlak models were used. KTrans and ve were increased, and the values of vp were decreased in the cerebral cortex and predilection sites for diffusion axonal injury. These findings are indicative of BBB disruption following TBI. (4) Conclusions: Our analysis supports the possibility of utilizing DCE-MRI for the detection of BBB disruption following TBI.

scholarly journals Contrast enhanced magnetic resonance imaging highlights neurovasculature changes following experimental traumatic brain injury in the rat

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
David K. Wright ◽  
Jamie N. Mayo ◽  
Mujun Sun ◽  
Terence J. O’Brien ◽  
Sandy R. Shultz
Keyword(s):  
Magnetic Resonance Imaging ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Magnetic Resonance ◽  
Female Rats ◽  
Resonance Imaging ◽  
Male And Female Rats ◽  
Cerebrovascular Function ◽  
Contrast Enhanced ◽  
Males And Females

AbstractNeurovascular injury has been proposed as a universal pathological hallmark of traumatic brain injury (TBI) with molecular markers of angiogenesis and endothelial function associated with injury severity and morbidity. Sex differences in the neurovasculature response post-TBI may contribute to the differences seen in how males and females respond to injury. Steady-state contrast enhanced magnetic resonance imaging (SSCE-MRI) can be used to non-invasively assess the neurovasculature and may be a useful tool in understanding and predicting outcomes post-TBI. Here we used SSCE-MRI to investigate the neurovasculature of male and female rats at 48 h after an experimental TBI, and how these changes related to neuromotor function at 1-week post-TBI. In addition to TBI induced changes, we found that female rats had greater vessel density, greater cerebral blood volumes and performed better on a neuromotor task than their male counterparts. These results suggest that acute post-TBI cerebrovascular function is worse in males, and that this may contribute to the greater functional deficits observed post-injury. Furthermore, these results highlight the potential of SSCE-MRI to provide insights into the cerebral microvasculature post-TBI. Future studies, incorporating both males and females, are warranted to investigate the evolution of these changes and the underlying mechanisms.

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