Expression of multiple plasma membrane Ca2+-ATPases in rat pancreatic islet cells

Cell Calcium ◽  
2000 ◽  
Vol 27 (4) ◽  
pp. 231-246 ◽  
Author(s):  
A. Kamagate ◽  
A. Herchuelz ◽  
A. Bollen ◽  
F.Van Eylen
Keyword(s):  
Plasma Membrane ◽  
Pancreatic Islet ◽  
Islet Cells ◽  
Pancreatic Islet Cells ◽  
Rat Pancreatic Islet

Dietary fatty acids modify insulin secretion of rat pancreatic islet cells in vitro

2002 ◽  
Vol 25 (5) ◽  
pp. 436-441 ◽  
Author(s):  
F. J. Tinahones ◽  
A. Pareja ◽  
F. J. Soriguer ◽  
J. M. Gómez-Zumaquero ◽  
F. Cardona ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Insulin Secretion ◽  
Pancreatic Islet ◽  
Islet Cells ◽  
Dietary Fatty Acids ◽  
Pancreatic Islet Cells ◽  
Rat Pancreatic Islet

Rat pancreatic islet cells in primary culture: occurrence of giant cells amenable to patch clamping

1985 ◽  
Vol 41 (1) ◽  
pp. 116-118
Author(s):  
D. A. Mathers ◽  
A. M. J. Buchan ◽  
J. C. Brown ◽  
S. C. Otte ◽  
L. K. J. Sikora
Keyword(s):  
Primary Culture ◽  
Pancreatic Islet ◽  
Islet Cells ◽  
Giant Cells ◽  
Pancreatic Islet Cells ◽  
Patch Clamping ◽  
Rat Pancreatic Islet

Development of rat pancreatic islet cells in vitro

1998 ◽  
Vol 43 (4) ◽  
pp. 306-312
Author(s):  
Hue-Lee Cheng Kaung ◽  
Chen Ya Wang ◽  
Wen-Wha Chen
Keyword(s):  
Pancreatic Islet ◽  
Islet Cells ◽  
Pancreatic Islet Cells ◽  
Rat Pancreatic Islet

Calcium exchangeability in subcellular fractions of pancreatic islet cells

1980 ◽  
Vol 41 (1) ◽  
pp. 233-243
Author(s):  
J.L. Borowitz ◽  
E.K. Matthews
Keyword(s):  
Secretory Granule ◽  
Pancreatic Islet ◽  
Islet Cells ◽  
Mitochondrial Fraction ◽  
Pancreatic Islet Cells ◽  
Subcellular Compartments ◽  
Granule Fraction ◽  
And Control ◽  
Insulin Secretory Granule ◽  
Rat Pancreatic Islet

The distribution and exchangeability of calcium within subcellular compartments of rat pancreatic islet cells was determined in pulse-chase experiments following isotopic labelling with 45Ca2+. In unstimulated islets the mitochondrial fraction showed the greatest, and the insulin secretory granule fraction the least, uptake of 45Ca2+; subsequently the rate of loss from each compartment during 120 min was in the order mitochondrial greater than microsomal greater than secretory granule fraction. On exposure to D-glucose, 16.8 mM, the 45Ca labelling of all 3 subcellular compartments was increased after 5 and 30 min stimulation. In contrast, theophylline 10 mM caused a significant decrease in mitochondrial 45Ca content with little effect on other compartments. These results are discussed in relation to the importance of calcium disposition, exchangeability, and mobility for the initiation and control of insulin secretion.

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