Background/Aim. Endoscopic mucosal resection (EMR) or mucosectomy is an
interventional procedure for minimal invasive endoscopic removal of benign
and malignant digestive tract tumors. Mucosectomy removes flat and sessile
neoplasms, early colorectal cancer (CRC) confined to mucosa or submucosa and
lateral spreading tumors. The aim of the study was to show our first
experience in application of this procedure in everyday practice in regarding
completeness and efficacy of the procedure, complication rate and incidence
of recurrent adenomas. Methods. In the prospective study 51 colorectal
adenomas were removed in 44 patients by EMR. Results. Single mucosectomy was
done in 43 patients, while multiple (8) in one patient. Complete resection
was obtained in all procedures. In 36 (68.62%) procedures ?en block?
resection was done, but in 15 (31.37%) procedures ?piece meal? resection was
performed. Synchronous colorectal tumors (benign or malignant) were detected
in 20 (45.45%) patients. Moderate dysplasia was found in 30 (58.82%)
adenomas, but high grade dysplasia in 9 (17.64%) of adenomas. Intramucosal
CRC was detected in 11.77% of adenomas. A total of 37 (72.54%) advanced
adenomas were removed. There were 3 (5.88%) of recurrent adenomas, 6-30
months after the EMR. Only one (2.2%) case of post procedure bleeding was
observed. Conclusion: EMR is a safe and efficious method for removal of flat,
sessile adenomas, as well as early CRC. EMR is a routine endoscopic procedure
in everyday practice of interventional endoscopist.