Chiron approach for the total synthesis of brevipolide M
Keyword(s):
One Pot
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An efficient stereoselective synthesis of brevipolide M was established in 13 linear steps and 17.8% overall yields base on chiron approach. The key steps of our synthesis involved tandem homologation / tetrahydrofuran cyclization and sequential ring-closing metathesis (RCM) / double-bond migration in one-pot processes.
Keyword(s):
Keyword(s):
2018 ◽
Vol 13
(7)
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pp. 1934578X1801300
Keyword(s):
2011 ◽
Vol 133
(24)
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pp. 9232-9235
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2016 ◽
Vol 14
(39)
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pp. 9287-9293
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2019 ◽
Vol 14
(1)
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pp. 1934578X1901400