New insights into surgical atrial fibrillation ablation therapy: Initial experience with a novel permanently implantable heart rhythm monitor device

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
T Hanke ◽  
M Misfeld ◽  
A Karluss ◽  
EI Charitos ◽  
I Neumeier ◽  
...  
Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Thorsten Hanke ◽  
Antje Karlub ◽  
Efstratios Charitos ◽  
Axel Hagemann ◽  
Bernhard Graf ◽  
...  

Introduction: Surgical atrial fibrillation (AF) therapy is gaining widespread acceptance among cardiothoracic surgeons. However, assessment of therapy success is until now solely based on short time -“snapshot”-rhythm surveillance often at irregular time intervals. In order to evaluate the ablation’s success we intraindividually compared two different types of follow-up strategies: conventional 24h-Holter monitoring and direct long time rhythm surveillance achieved by a new implantable monitor device (IRMD). Methods: 20 cardiac surgical patients (male 16, mean age 69±9y) with a mean AF of 30±48m (paroxysmal n=7, persistent n=9, long standing persistent n=4) were treated intraoperatively with epicardial high intensity focus ultrasound (HIFU) ablation (+CABG n=10, +AVR n=5, +AVR/CABG n=2, +valve preserving ascending aorta replacement n=2, +endoaneurymoraphy n=1, lone atrial fibrillation n=1). Postoperative heart rhythm monitoring was accomplished in all patients with a 24h-Holter-monitor at prescheduled time intervals and additionally with a new implantable monitor device (Reveal XT, Medtronic®, MN, USA). A more than 0.5% of “time in AF” as reported by the IRMD was considered as recurrence of AF. Telemetry of the IRMD was performed simultaneously after completion of 24h-Holter monitoring. Results: During a mean FU of 8.7±1.4m a total of 29 24 h-Holter-monitors were obtained. Sinus rhythm was documented in 21, the IMRD however revealed AF recurrence in 11 of these cases. Thus, conventional 24 h ECG monitoring failed to identify AF recurrence in 59% of cases (p<0.027). Success rate after surgical ablation therapy (defined as freedom from AF recurrence of more than 0.5% of observational period) was 72% with 24h Holter monitoring, but only 35% using continuous ECG monitoring with IRMD. Conclusion: In order to evaluate better “real life” outcomes after atrial fibrillation ablation therapy, long term continuous heart rhythm surveillance instead of -“snapshot” - heart rhythm monitoring is mandatory. This is particularly important for the decision to alter medical therapies, e.g. oral anticoagulation or antiarrhythmic treatment.


EP Europace ◽  
2017 ◽  
Vol 19 (suppl_3) ◽  
pp. iii181-iii181
Author(s):  
M. Riemann ◽  
NCF Sandgaard ◽  
J. Dalhoj ◽  
S. Djurhuus ◽  
JB. Johansen ◽  
...  

EP Europace ◽  
2012 ◽  
Vol 14 (8) ◽  
pp. 1094-1103 ◽  
Author(s):  
E. Arbelo ◽  
J. Brugada ◽  
G. Hindricks ◽  
A. Maggioni ◽  
L. Tavazzi ◽  
...  

EP Europace ◽  
2019 ◽  
Vol 22 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Mihaela Grecu ◽  
Carina Blomström-Lundqvist ◽  
Josef Kautzner ◽  
Cecile Laroche ◽  
Isabelle C Van Gelder ◽  
...  

Abstract Aim The purpose of this study was to compare sex differences of atrial fibrillation (AF) catheter ablation (CA) and to analyse the opportunities for improved outcomes. Methods and results All data were collected from the Atrial Fibrillation Ablation Long-Term registry, a prospective, multinational study conducted by the ESC-EORP European Heart Rhythm Association (EHRA) under the EURObservational Research Programme (ESC-EORP). A total of 104 centres in 27 European countries participated. Of 3593 included patients, 1146 (31.9%) were female. Female patients were older (61.0 vs. 56.4 years; P &lt; 0.001), had more comorbidities (hypertension, diabetes, and obesity), more episodes of arrhythmias per month (6.9 vs. 6.2; P &lt; 0.001), and a higher average EHRA score (2.6 vs. 2.4; P &lt; 0.001). The duration of the procedure was shorter in females (160.1 min vs. 167.9 min; P &lt; 0.001), irrespective of additional ablation lesions added to pulmonary vein isolation. Overall cardiovascular complications were more frequent in women than in men (5.7% vs. 3.4%; P &lt; 0.001). Furthermore, cardiac perforations (3.8% vs. 1.3%; P = 0.011) and neurological complications (2.2% vs. 0.3%; P = 0.004) were found in females in less experienced centres than in experienced ones. On a final note, at 12 months, AF recurrence rate was similar in females and males (34.4% vs. 34.2%; P = 0.897), but more females were still on antiarrhythmic drugs (50.6% vs. 44.1%; P &lt; 0.001) when compared with men. Conclusion Females underwent CA procedures for AF less frequently than males throughout Europe, despite more recurrent symptoms. With the same success rate, severe acute complications remained considerable in females, especially in less experienced centres.


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