Diabetes mellitus is a difficult metabolic disorder that has seriously impact the human health and quality of life. Medicinal
plants are being used to control diabetes However, they are not entirely effective and no one has ever been reported to have
fully recovered from diabetes. Many plants have been used for the management of diabetes mellitus in various traditional
systems of medicine worldwide as they are a great source of biological constituents and many of them are known to be
effective against diabetes. Medicinal plants with antihyperglycemic activities are being more desired, owing to lesser sideeffects
and low cost. Streptozotocin was induced to all groups of rats at dosage of 35 -55mg/kg except for the normal.
Streptozotocin induced diabetes in sprague dawly rats were used to study antidiabetic activity of methonolic extract of
two medicinal plants Gymnema sylvestre,Andrographis paniculata methanolic leaf extract was administered orally in
graded doses of 30 mg/kg,50mg /kg sprague dawly rats Gymnema sylvestre at a dose of 30mg/kg and Andrographis
paniculata at a dose of 50mg/kg showed significant anti-hyperglycemic and anti-oxidative effect which was evident from
the 1st week of treatment.
Evaluation of antidiabetic and related actions of some Indian medicinal plants in diabetic rats
